ArticleThe Plant cell2011
AUXIN RESPONSE FACTOR8 regulates Arabidopsis petal growth by interacting with the bHLH transcription factor BIGPETALp.
Article in The Plant cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers.
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134 citing papers in PubMed, 263 citations in OpenAlex.
- The miR167-ARF8 module coordinates stamen-pistil development and fruit set in tomato.The New phytologist · 2026Article
- Insights into the genetic bases of differential organ size in cactus flowers: a case study in two contrasting species.Annals of botany · 2026Article
- Histone deacetylation links jasmonic acid signaling to flower size control in rose.Molecular horticulture · 2026Article
- The Auxin-Induced Protein Gene (MsARG4) Regulates Rapid Stem Elongation and Nutritional Quality Enhancement in Alfalfa.Plants (Basel, Switzerland) · 2026Article
- Mutational analyses of an instability domain reveal its conserved role in the regulation of class-B ARF levels inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- MONOPTEROS isoform MP11ir plays a role during somatic embryogenesis in Arabidopsis thaliana.Plant physiology · 2025Article
- Comprehensive Analysis of the ARF Gene Family Reveals Their Roles in Chinese Chestnut (Biology · 2025Article
- Genome-Wide Analysis and Expression Profiles of Auxin Response Factors in Ginger (International journal of molecular sciences · 2025Article
- Discovery of Hub Genes Involved in Seed Development and Lipid Biosynthesis in Sea Buckthorn (Plants (Basel, Switzerland) · 2025Article
- Article
- Transcriptome analysis reveals the mechanisms underlying petal growth during the flower opening process in Phalaenopsis orchids.BMC plant biology · 2025Article
- Genome-Wide Identification ofInternational journal of molecular sciences · 2025Article
- Transcriptome Analysis Reveals Association of E-Class AmMADS-Box Genes with Petal Malformation inInternational journal of molecular sciences · 2025Article
- Integrated endogenous hormones and transcriptome analysis contribute to fruit development related gene mining in Eriobotrya japonica.Scientific reports · 2025Article
- Anthocyanins and Anthocyanin Biosynthesis Gene Expression inPlants (Basel, Switzerland) · 2025Article
- Building beauty: Understanding how hormone signaling regulates petal patterning and morphogenesis.The Plant journal : for cell and molecular biology · 2025Review
- Pectin methylesterase inhibitor 58 negatively regulates ray petal elongation by inhibiting cell expansion in Gerbera hybrida.Plant cell reports · 2025Article
- Comparative transcriptomics of two petal variants reveals key functional genes underlying petal shape development in lotus (Frontiers in plant science · 2025Article
- AUXIN RESPONSE FACTOR 2 mediates repression of strawberry receptacle ripening via auxin-ABA interplay.Plant physiology · 2024Article
- Clock protein LHY targetsScience advances · 2024Article
74 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant organ growth and final size are determined by coordinated cell proliferation and expansion. The BIGPETALp (BPEp) basic helix-loop-helix (bHLH) transcription factor was shown to limit Arabidopsis thaliana petal growth by influencing cell expansion. We demonstrate here that BPEp interacts with AUXIN RESPONSE FACTOR8 (ARF8) to affect petal growth. This interaction is mediated through the BPEp C-terminal domain (SD(BPEp)) and the C-terminal domain of ARF8. Site-directed mutagenesis identified an amino acid consensus motif in SD(BPEp) that is critical for mediating BPEp-ARF8 interaction. This motif shares sequence similarity with motif III of ARF and AUXIN/INDOLE-3-ACETIC ACID proteins. Petals of arf8 mutants are significantly larger than those of the wild type due to increased cell number and increased cell expansion. bpe arf8 double mutant analyses show that during early petal development stages, ARF8 and BPEp work synergistically to limit mitotic growth. During late stages, ARF8 and BPEp interact to limit cell expansion. The alterations in cell division and cell expansion observed in arf8 and/or bpe mutants are associated with a change in expression of early auxin-responsive genes. The data provide evidence of an interaction between an ARF and a bHLH transcription factor and of its biological significance in regulating petal growth, with local auxin levels likely influencing such a biological function.
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