Evidence map›Paper›PMID 21420791›Full record

SynthesisAddictive behaviors2011

Do smoking reduction interventions promote cessation in smokers not ready to quit?

Taghrid Asfar, Jon O Ebbert, Robert C Klesges, George E Relyea

Registry-linked trialOpen access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Addictive behaviors, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02491086 (Motivating Smokers at Outdoor Public Smoking Hotspots to Have Quit Attempt With Nicotine Replacement Therapy Sampling), which is not on this map. Cited by 58 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 5 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02491086 nacompletednot on this mapstarted 2015, after this paper: background citation

Motivating Smokers at Outdoor Public Smoking Hotspots to Have Quit Attempt With Nicotine Replacement Therapy Sampling: A Randomized Controlled Trial

TypeinterventionalSponsorThe University of Hong KongRan2015 to 2016Enrolled100ConditionsSmoking CessationArmsNicotine replacement therapy (NRT) sampling, Smoking cessation counseling
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 5 syntheses or guidelines pooled it, 109 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Interventions to reduce harm from continued tobacco use.The Cochrane database of systematic reviews · 2016
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Reengagement for Long-Term Smoking-Cessation In Military Personnel, Retirees, Family Members (TRICARE): A Randomized Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Trial
  8. Trial
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  10. Exploratory Analyses of the Popularity and Efficacy of Four Behavioral Methods of Gradual Smoking Cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Trial
  11. Trial
  12. Trial
  13. Trial
  14. A Mediation Analysis of Motivational, Reduction, and Usual Care Interventions for Smokers Who Are Not Ready to Quit.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Trial
  20. Efficacy of a tobacco quitline among adult survivors of childhood cancer.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2015
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Taghrid AsfarDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. taghrid.asfar@stjude.org
Jon O Ebbert
Robert C Klesges
George E Relyea
St. Jude Children's Research Hospital · USUniversity of Memphis · USWinnMed · US

Funding

POPULATION WIDE SMOKING CESSATION/PREVENTION PROGRAMR18HL053478 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI KLESGES, ROBERT C · 1999 to 2012
$5.1M
Efficacy of a Tobacco Quit Line for Childhood Cancer SurvivorsR01CA127964 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KLESGES, ROBERT C · 2008 to 2012
$3.1M
POPULATION WIDE SMOKING CESSATION/PREVENTION PROGRAMR01HL053478 · NHLBI · UNIVERSITY OF MEMPHIS · PI KLESGES, ROBERT C · 1995 to 1997
–
NCI NIH HHS CA127964NCI NIH HHS R01 CA127964NHLBI NIH HHS HL053478NHLBI NIH HHS R18 HL053478
6 · The paper itself

Abstract

backgroundLimited treatment options exist for smokers who are not ready to make a quit attempt. Smoking reduction may be a viable treatment approach if proven to increase the rates of long-term abstinence from smoking.

methodA systematic review of randomized, controlled trials that tested smoking-reduction interventions (pharmacological, behavioral, or both combined) among smokers who were not ready to make a quit attempt (immediately or in the next month) was conducted to assess the efficacy of these strategies in promoting future smoking abstinence. The primary outcome was the 7-day point-prevalence smoking abstinence at longest follow-up (≥6months). Ten trials were included; six tested pharmacologic interventions, one evaluated a behavioral intervention, and three evaluated combined interventions.

resultsPharmacologic (2732 participants; OR 2.33, 95% CI 1.43 to 3.79) and combined (638 participants; OR 2.14, 95% CI: 1.28 to 3.60) smoking-reduction interventions significantly increased long-term abstinence from smoking. Insufficient evidence was available on the efficacy of behavioral smoking-reduction interventions (320 participants; OR 1.49, 95% CI 0.56 to 3.93).

conclusionsFurther research to evaluate the efficacy of smoking reduction should have cessation as an endpoint, focus on clarity and consistency in patient selection, and identify the mechanism through which nicotine replacement therapy assisted smoking reduction in increasing abstinence rates.

Indexed as

Behavior TherapyHumansPatient ComplianceRandomized Controlled Trials as TopicSmokingSmoking CessationTreatment OutcomeTreatment Refusal

Identifiers

PMID21420791
PMCPMC3081955
OpenAlexW2081287796

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.