Evidence map›Paper›PMID 21420743›Full record

ReviewTrends in neurosciences2011

Routes, destinations and delays: recent advances in AMPA receptor trafficking.

Jeremy M Henley, Ellen A Barker, Oleg O Glebov

Abstract readReview
In one paragraph

Review in Trends in neurosciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Synthesis of [Molecules (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Review
  10. Structural Design of Multidentate Copolymers as Compact Quantum Dot Coatings for Live-Cell Single-Particle Imaging.Chemistry of materials : a publication of the American Chemical Society · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Antibodies Against the NHFrontiers in immunology · 2021
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Modulation of AMPA Receptors by Nitric Oxide in Nerve Cells.International journal of molecular sciences · 2020
    Review
  20. Phosphorylation-Dependent Regulation of CaFrontiers in synaptic neuroscience · 2020
    Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jeremy M HenleyMRC Centre for Synaptic Plasticity, School of Biochemistry, University of Bristol, University Walk, Bristol, UK, BS8 1TD. j.m.henley@bristol.ac.uk
Ellen A Barker
Oleg O Glebov

Funding

Medical Research Council G0601810Medical Research Council G0601810(80974)Wellcome Trust 083721
6 · The paper itself

Abstract

Postsynaptic AMPA-type glutamate receptors (AMPARs) mediate most fast excitatory synaptic transmission and are crucial for many aspects of brain function, including learning, memory and cognition. The number, synaptic localization and subunit composition of synaptic AMPARs are tightly regulated by network activity and by the history of activity at individual synapses. Furthermore, aberrant AMPAR trafficking is implicated in neurodegenerative diseases. AMPARs therefore represent a prime target for drug development and the mechanisms that control their synaptic delivery, retention and removal are the subject of extensive research. Here, we review recent findings that have provided new insights into AMPAR trafficking and that might lead to the development of novel therapeutic strategies.

Indexed as

AnimalsBrainHumansModels, NeurologicalNeuronsProtein TransportReceptors, AMPASynapsesSynaptic TransmissionReceptors, AMPA

Identifiers

PMID21420743
PMCPMC3314507

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.