ArticleRegulatory toxicology and pharmacology : RTP2011
AllerML: markup language for allergens.
Article in Regulatory toxicology and pharmacology : RTP, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Enhancing allergenicity risk assessment for novel foods in the EU: insights from the updated EFSA guidance - requirements, knowledge gaps and research needs.Frontiers in toxicology · 2025Review
- A reverse vaccinology approach on transmembrane carbonic anhydrases from Plasmodium species as vaccine candidates for malaria prevention.Malaria journal · 2022Article
- Still SDAPing Along: 20 Years of the Structural Database of Allergenic Proteins.Frontiers in allergy · 2022Article
- The COMPARE Database: A Public Resource for Allergen Identification, Adapted for Continuous Improvement.Frontiers in allergy · 2021Article
- Development and Challenges of Antimicrobial Peptides for Therapeutic Applications.Antibiotics (Basel, Switzerland) · 2020Review
- Modeling-Enabled Systems Nutritional Immunology.Frontiers in nutrition · 2016Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Many concerns have been raised about the potential allergenicity of novel, recombinant proteins into food crops. Guidelines, proposed by WHO/FAO and EFSA, include the use of bioinformatics screening to assess the risk of potential allergenicity or cross-reactivities of all proteins introduced, for example, to improve nutritional value or promote crop resistance. However, there are no universally accepted standards that can be used to encode data on the biology of allergens to facilitate using data from multiple databases in this screening. Therefore, we developed AllerML a markup language for allergens to assist in the automated exchange of information between databases and in the integration of the bioinformatics tools that are used to investigate allergenicity and cross-reactivity. As proof of concept, AllerML was implemented using the Structural Database of Allergenic Proteins (SDAP; http://fermi.utmb.edu/SDAP/) database. General implementation of AllerML will promote automatic flow of validated data that will aid in allergy research and regulatory analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.