ReviewTranslational research : the journal of laboratory and clinical medicine2011
MicroRNAs in cardiac disease.
Review in Translational research : the journal of laboratory and clinical medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 75 citations in OpenAlex.
- Circulating Pro-Inflammatory Exosomes Worsen Stroke Outcomes in Aging.Circulation research · 2021Article
- Analysis ofReports of biochemistry & molecular biology · 2020Article
- Downregulated microRNA‑133a induces HUVECs injury: Potential role of the (pro) renin receptor in angiotensin II‑dependent hypertension.Molecular medicine reports · 2019Article
- Systematic review and critique of circulating miRNAs as biomarkers of stage I-II non-small cell lung cancer.Oncotarget · 2017Review
- A Systems Biology Approach to Investigating Sex Differences in Cardiac Hypertrophy.Journal of the American Heart Association · 2017Article
- Exercise for cardiac health and regeneration: killing two birds with one stone.Annals of translational medicine · 2017Article
- Calcific Aortic Valve Disease: Part 2-Morphomechanical Abnormalities, Gene Reexpression, and Gender Effects on Ventricular Hypertrophy and Its Reversibility.Journal of cardiovascular translational research · 2016Review
- Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION.The Journal of biological chemistry · 2016Article
- Molecular mechanisms of cardiovascular benefits of exercise: Running for cover from heart disease.Global cardiology science & practice · 2016Article
- Cellular and Molecular Aspects of Dyssynchrony and Resynchronization.Cardiac electrophysiology clinics · 2015Review
- Enhanced Cardiac Regenerative Ability of Stem Cells After Ischemia-Reperfusion Injury: Role of Human CD34+ Cells Deficient in MicroRNA-377.Journal of the American College of Cardiology · 2015Article
- Transcriptome microRNA profiling of bovine mammary glands infected with Staphylococcus aureus.International journal of molecular sciences · 2015Article
- MicroRNAs in pediatric central nervous system embryonal neoplasms: the known unknown.Journal of hematology & oncology · 2015Review
- Systems analysis reveals down-regulation of a network of pro-survival miRNAs drives the apoptotic response in dilated cardiomyopathy.Molecular bioSystems · 2015Article
- Bedside-to-Bench Translational Research for Chronic Heart Failure: Creating an Agenda for Clients Who Do Not Meet Trial Enrollment Criteria.Clinical Medicine Insights. Cardiology · 2015Review
- Review
- Lost in Translation (LiT): IUPHAR Review 6.British journal of pharmacology · 2014Review
- Identification of suitable reference genes for hepatic microRNA quantitation.BMC research notes · 2014Article
- Proteogenomics of selective susceptibility to endotoxin using circulating acute phase biomarkers and bioassay development in sheep: a review.Proteome science · 2014Article
- MicroRNAs in heart failure: Small molecules with major impact.Global cardiology science & practice · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
MicroRNAs (miRs) are transcriptionally regulated single-strand RNAs that depress protein expression through posttranscriptional mRNA silencing. A host of recent studies have established essential roles for miRs in cardiac development and cardiac health. Regulated myocardial miR expression is observed in a variety of cardiac syndromes, and serum miR levels are being evaluated as disease biomarkers. The manipulation of miR levels in mouse hearts using genetic techniques or engineered miR mimetics and antagonists is elucidating the roles of specific cardiac miRs in cardiac development, and in the cardiac response to injury or stress, and heart disease. The ability to target multiple factors within a single biological response pathway by a given miR has prompted the development of small miR-targeting molecules that can be readily delivered and have sustained in vivo effects. These advances establish a foundation for novel diagnostics and new therapeutic approaches for myocardial infarction, cardiac hypertrophy, and heart failure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.