Evidence map›Paper›PMID 21419877›Full record

ReviewNanomedicine : nanotechnology, biology, and medicine2011

Upconversion nanoparticles: synthesis, surface modification and biological applications.

Meng Wang, Gopal Abbineni, April Clevenger, Chuanbin Mao, Shukun Xu

Abstract readReview
In one paragraph

Review in Nanomedicine : nanotechnology, biology, and medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed.

  1. Upconversion Colloid for Tracking Cellular Uptake of Nanoparticles.International journal of molecular sciences · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. SCN-IgG functionalized NaYFRSC advances · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Externally triggered drug delivery systems.Smart materials in medicine · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meng WangCollege of Sciences, Northeastern University, Shenyang, People's Republic of China.
Gopal Abbineni
April Clevenger
Chuanbin Mao
Shukun Xu

Funding

Phage-inspired nanoparticles with genetically tunable target-specificityR01HL092526 · NHLBI · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2009 to 2010
$806k
Phage-Mimetic Nanorods for Targeted Breast Cancer TreatmentR21EB009909 · NIBIB · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2009 to 2010
$399k
Bone-seeking and cell-targeting non-viral vectors for BMP-2 gene deliveryR03AR056848 · NIAMS · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2009 to 2011
$222k
NHLBI NIH HHS R01 HL092526NHLBI NIH HHS R01HL092526-01A2NIAMS NIH HHS R03 AR056848NIAMS NIH HHS R03AR056848-01NIBIB NIH HHS R21 EB009909NIBIB NIH HHS R21EB009909-01A1
6 · The paper itself

Abstract

New generation fluorophores, also termed upconversion nanoparticles (UCNPs), have the ability to convert near infrared radiations with lower energy into visible radiations with higher energy via a nonlinear optical process. Recently, these UCNPs have evolved as alternative fluorescent labels to traditional fluorophores, showing great potential for imaging and biodetection assays in both in vitro and in vivo applications. UCNPs exhibit unique luminescent properties, including high penetration depth into tissues, low background signals, large Stokes shifts, sharp emission bands, and high resistance to photobleaching, making UCNPs an attractive alternative source for overcoming current limitations in traditional fluorescent probes. In this article, we discuss the recent progress in the synthesis and surface modification of rare-earth doped UCNPs with a specific focus on their biological applications. FROM THE CLINICAL EDITOR: Upconversion nanoparticles - a new generation of fluorophores - convert near infrared radiations into visible radiations via a nonlinear optical process. These UCNPs have evolved as alternative fluorescent labels with great potential for imaging and biodetection assays in both in vitro and in vivo applications.

Indexed as

AnimalsDiagnostic ImagingFluorescent DyesHumansMetals, Rare EarthMicroscopy, FluorescenceNanoparticlesNanotechnologySurface PropertiesFluorescent DyesMetals, Rare Earth

Identifiers

PMID21419877
PMCPMC3166393

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.