Evidence map›Paper›PMID 21419576›Full record

ArticleAddictive behaviors2011

Exposure to smoking cues: cardiovascular and autonomic effects.

Joel Erblich, Dana H Bovbjerg, Richard P Sloan

Abstract read
In one paragraph

Article in Addictive behaviors, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Cue-induced Magnetic Resonance Spectroscopy of Glutamate in Addiction Research: Current Evidence, Pros, and Cons.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
    Review
  7. Systemic physiological "noise" in fMRI has clinical relevance.medRxiv : the preprint server for health sciences · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Response Time to Craving-Item Ratings as an Implicit Measure of Craving-Related Processes.Clinical psychological science : a journal of the Association for Psychological Science · 2015
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joel ErblichMount Sinai School of Medicine, New York, NY, United States. joel.erblich@mssm.edu
Dana H Bovbjerg
Richard P Sloan

Funding

MOUNT SINAI INSTITUTES FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR029887 · NCRR · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SAMPSON, HUGH A · 2009 to 2011
$19.2M
Stress-Induced Craving and Smoking Cessation: Effects of Dopamine-related GenesK22CA124800 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ERBLICH, JOEL · 2007 to 2009
$469k
Dopamine Genotypes, Experimentally-induced Craving, & Cessation in Female SmokersR21CA118703 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ERBLICH, JOEL · 2007 to 2008
$373k
NCI NIH HHS K22 CA124800NCI NIH HHS K22CA124800NCI NIH HHS R21 CA118703NCI NIH HHS R21CA118703NCRR NIH HHS UL1 RR029887NCRR NIH HHS UL1RR029887
6 · The paper itself

Abstract

Laboratory exposures to smoking cues have been shown to reliably induce self-reported cigarette cravings among smokers, a model of environmentally triggered urges to smoke that can contribute to poorer cessation success. Several studies have also demonstrated that cue exposures give rise to changes in heart rate and blood pressure. Few studies, however, have investigated possible cue effects on heart rate and blood pressure variability (HRV and BPV). Particularly intriguing in this regard are cardiac oscillations in the low (i.e., 0.04-0.15 Hz), and high (i.e., 0.15-0.50 Hz) frequency range, which are thought to reflect components of autonomic control and response to environmental challenges. A closer examination of cardiovascular reactivity may thus help characterize the autonomic response to smoking cue exposure. To that end, an experimental study was conducted in which nicotine dependent daily smokers (n=98) were exposed to guided imagery of neutral and smoking situations, while continuous, noninvasive, beat-to-beat cardiovascular data were collected. Consistent with previous research, the findings revealed significant increases in both systolic and diastolic blood pressure during smoking imagery, relative to neutral imagery. In addition, power spectral density analyses of heart rate and blood pressure variability revealed elevated HRV and BPV in both the low- and high-frequency ranges during the smoking imagery. The results suggest the presence of an autonomic component to smoking cue reactivity, and also raise the possibility of long-term negative cardiac consequences for smokers who ubiquitously encounter cues in their daily environments.

Indexed as

CuesAdultAutonomic Nervous SystemBehavior, AddictiveBlood PressureFemaleHeart RateHumansImagery, PsychotherapyMaleMiddle AgedSmoking

Identifiers

PMID21419576
PMCPMC3095102

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.