ArticleAmerican journal of obstetrics and gynecology2011
The association between early life adversity and bacterial vaginosis during pregnancy.
Article in American journal of obstetrics and gynecology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Childhood abuse and perinatal outcomes for mother and child: A systematic review of the literature.PloS one · 2024Pooled it
- Social, microbial, and immune factors linking bacterial vaginosis and infectious diseases.The Journal of clinical investigation · 2025Review
- Sexual violence history predicts changes in vaginal immune parameters during sexual arousal.Brain, behavior, and immunity · 2022Article
- Integrative Review of Early Life Adversity and Cortisol Regulation in Pregnancy.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN · 2021Review
- Explaining the Black-White Disparity in Preterm Birth: A Consensus Statement From a Multi-Disciplinary Scientific Work Group Convened by the March of Dimes.Frontiers in reproductive health · 2021Review
- Vaginal Microbiome Composition in Early Pregnancy and Risk of Spontaneous Preterm and Early Term Birth Among African American Women.Frontiers in cellular and infection microbiology · 2021Article
- The transgenerational transmission of maternal adverse childhood experiences (ACEs): Insights from placental aging and infant autonomic nervous system reactivity.Psychoneuroendocrinology · 2019Article
- Translating basic research knowledge on the biological embedding of early-life stress into novel approaches for the developmental programming of lifelong health.Psychoneuroendocrinology · 2019Review
- Associations Between Maternal Exposure to Child Abuse, Preterm Birth, and Very Preterm Birth in Young, Nulliparous Women.Maternal and child health journal · 2019Article
- An exploratory study of whether pregnancy outcomes influence maternal self-reported history of child maltreatment.Child abuse & neglect · 2018Observational
- Intergenerational Effect of Maternal Exposure to Childhood Maltreatment on Newborn Brain Anatomy.Biological psychiatry · 2018Article
- Childhood maltreatment is associated with increased risk of subclinical hypothyroidism in pregnancy.Psychoneuroendocrinology · 2017Article
- Maternal exposure to childhood maltreatment and risk of stillbirth.Annals of epidemiology · 2017Article
- Protocol for the Emory University African American Vaginal, Oral, and Gut Microbiome in Pregnancy Cohort Study.BMC pregnancy and childbirth · 2017Article
- Intergenerational Transmission of Maternal Childhood Maltreatment Exposure: Implications for Fetal Brain Development.Journal of the American Academy of Child and Adolescent Psychiatry · 2017Review
- Article
- Post-traumatic stress in pregnant women with primary cytomegalovirus infection and risk of congenital infection in newborns.BJPsych open · 2016Article
- The Interplay of Host Immunity, Environment and the Risk of Bacterial Vaginosis and Associated Reproductive Health Outcomes.The Journal of infectious diseases · 2016Review
- Maternal Exposure to Childhood Trauma Is Associated During Pregnancy With Placental-Fetal Stress Physiology.Biological psychiatry · 2016Article
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThe purpose of this study was to examine associations between chronic preconception psychosocial and socioeconomic stress with bacterial vaginosis (BV) during pregnancy. STUDY
designUsing univariate and multivariate logistic regression, childhood abuse and neglect, chronic discrimination, childhood socioeconomic status, potential confounders, and BV were assessed at 14-16 and 19-22 weeks' gestation in a cohort of 312 pregnant women.
resultsPersistent BV (BV positive at both time points vs no BV at either time point) was associated with childhood sexual abuse (CSA), chronic discrimination, and lack of parental home ownership. These associations were still present after covarying for current perceived stress, socioeconomic status, and other potential confounders.
conclusionThere is evidence that BV during pregnancy is independently linked with early life psychosocial adversity, suggesting that a life-course perspective may be important in elucidating determinants of perinatal outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.