Evidence map›Paper›PMID 21418671›Full record

SynthesisBMJ clinical evidence2010

Diabetic nephropathy: preventing progression.

Michael Shlipak

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in BMJ clinical evidence, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07602478 (Short-term Effect of Eccentric Contraction Exercises in the Treatment of Patients With Shoulder Pain Syndrome), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07602478 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Short-term Effect of Eccentric Contraction Exercises in the Treatment of Patients With Shoulder Pain Syndrome: A Randomized Controlled Trial

TypeinterventionalSponsorRafeef Hassan AsiriRan2025 to 2026Enrolled60ConditionsShoulder Pain Syndrome, Rotator Cuff Syndrome, Rotator Cuff TendonitisArmsEccentric Training Protocol, Traditional Physical Therapy Only
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michael ShlipakEpidemiology & Biostatistics, San Francisco VA Medical Center, San Francisco, USA.
San Francisco VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUp to one third of people with type 1 or 2 diabetes will develop microalbuminuria or macroalbuminuria after 20 years. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of treatments in people with type 1 diabetes and early nephropathy? What are the effects of treatments in people with type 1 diabetes and late nephropathy? What are the effects of treatments in people with type 2 diabetes and early nephropathy? What are the effects of treatments in people with type 2 diabetes and late nephropathy? We searched: Medline, Embase, The Cochrane Library, and other important databases up to November 2009 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).

resultsWe found 19 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.

conclusionsIn this systematic review we present information relating to the effectiveness and safety of the following interventions: angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers, glycaemic control, protein restriction, and tight control of blood pressure.

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesAlbuminuriaAngiotensin-Converting Enzyme InhibitorsDisease ProgressionHumansAngiotensin-Converting Enzyme Inhibitors

Identifiers

PMID21418671
PMCPMC3217768
OpenAlexW196998920

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.