ArticleJournal of veterinary internal medicine
Variability in results of the microscopic agglutination test in dogs with clinical leptospirosis and dogs vaccinated against leptospirosis.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- A systematic review of leptospirosis on dogs, pigs, and horses in Latin America.Tropical animal health and production · 2017Pooled it
- A systematic review on the microscopic agglutination test seroepidemiology of bovine leptospirosis in Latin America.Tropical animal health and production · 2016Pooled it
- FiveMicroorganisms · 2025Article
- Presence of Vaccine-Induced Antibodies AgainstVaccines · 2025Article
- Grenadian cats as potential reservoir for Leptospira.PLoS neglected tropical diseases · 2024Article
- Navigating cross-reactivity and host species effects in a serological assay: A case study of the microscopic agglutination test for Leptospira serology.PLoS neglected tropical diseases · 2024Article
- Isolation of VirulentMicroorganisms · 2024Article
- Tracking potentialOne health (Amsterdam, Netherlands) · 2024Article
- Exudative glomerulonephritis associated with acute leptospirosis in dogs.Veterinary pathology · 2024Article
- The Presence of a Virulent Clone ofMicroorganisms · 2024Article
- Detection and Identification of PathogenicTransboundary and emerging diseases · 2024Article
- Leptospirosis in horses: Sentinels for a neglected zoonosis? A systematic review.Veterinary world · 2023Article
- Evaluation ofJournal of feline medicine and surgery · 2023Article
- Epidemiology of Leptospirosis: The First Literature Review of the Neglected Disease in the Middle East.Tropical medicine and infectious disease · 2022Review
- Canine Leptospirosis in a Northwestern Region of Colombia: Serological, Molecular and Epidemiological Factors.Pathogens (Basel, Switzerland) · 2022Article
- Circulating serogroups of Leptospira in swine from a 7-year study in France (2011-2017).Porcine health management · 2022Article
- The Evaluation of the Diagnostic Value of a PCR Assay When Compared to a Serologic Micro-Agglutination Test for Canine Leptospirosis.Frontiers in veterinary science · 2022Article
- Detection and characterization ofJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021Article
- Presence and Characterization of Zoonotic Bacterial Pathogens in Wild Boar Hunting Dogs (Animals : an open access journal from MDPI · 2021Article
- Clinical, diagnostic, and epidemiological features of a community-wide outbreak of canine leptospirosis in a low-prevalence region (Maricopa County, Arizona).Journal of the American Veterinary Medical Association · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe microscopic agglutination test (MAT) is commonly used for the diagnosis of canine leptospirosis. In dogs it is sometimes suggested that the serogroup with the highest MAT titer is the infecting serogroup; however, this is not true in humans with confirmed leptospirosis. We sought to investigate the value of MAT results in predicting the infecting serogroup by comparing results across several laboratories and within individual dogs over time.
objectivesTo examine the variability in MAT results across different laboratories in dogs recently vaccinated against leptospirosis, and in dogs with clinical leptospirosis, and to investigate variability over time in MAT results in individual dogs with leptospirosis. ANIMALS: Eighteen dogs from a research colony, 9 of which had been vaccinated against leptospirosis, and 17 dogs clinically diagnosed with leptospirosis.
methodsSerum samples were submitted to up to 5 veterinary diagnostic laboratories for MAT titers from each dog on at least 1 occasion. MAT results also were followed over time in 6 dogs diagnosed with leptospirosis.
resultsMAT results were discordant across different laboratories in dogs recently vaccinated against leptospirosis and in dogs with clinical leptospirosis. MAT results varied over time in individual dogs with the disease. CONCLUSIONS AND CLINICAL IMPORTANCE: The MAT is a valuable test for the diagnosis of leptospirosis in dogs, but it is unlikely that test results can be used to predict the infecting serogroup. Laboratories offering the MAT should consider participation in a proficiency scheme.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.