Evidence map›Paper›PMID 21415831›Full record

ReviewCurrent opinion in pediatrics2011

The intestinal microbiome of infants and the use of probiotics.

Flavia Indrio, Josef Neu

Erratum issuedOpen access · greenAbstract readReview
In one paragraph

Review in Current opinion in pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Inhibitory Effect ofDrug design, development and therapy · 2021
    Article
  4. Review
  5. Aggressive Nutrition of the Preterm Infant.Current pediatrics reports · 2013
    Article
  6. Robustness of gut microbiota of healthy adults in response to probiotic intervention revealed by high-throughput pyrosequencing.DNA research : an international journal for rapid publication of reports on genes and genomes · 2013
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Flavia IndrioUniversity of Bari, Bari, Italy.
Josef Neu
Florida College · USUniversity of Bari Aldo Moro · IT

Funding

Intestinal Microecology, Inflammatory Markers and Necrotizing EnterocolitisR01HD059143 · NICHD · UNIVERSITY OF FLORIDA · PI NEU, JOSEF · 2009 to 2013
$1.7M
NICHD NIH HHS R01 HD059143
6 · The paper itself

Abstract

purpose of reviewThe increasing use of probiotics in neonates deserves scrutiny of the therapeutic as well as potentially harmful effects of these bacteria. In this review we describe the possible application of probiotics in the more common diseases in the neonatal period. RECENT

findingsRecent advances in our capability to identify microbes and their function in the gastrointestinal tract offer exciting opportunities to discover the pathophysiology of enigmatic diseases such as necrotizing enterocolitis (NEC) and late-onset sepsis (LOS) in the neonate. The relationship of the resident intestinal microbes to neural and muscular processes such as intestinal motility and neurodevelopment are also being evaluated. SUMMARY: We focus on the possibility of the application of probiotics for disorders of motility in the infant, NEC and LOS. Here we will summarize some of the recent advances in these areas as they relate to clinical practice and discuss areas where additional research is needed.

Indexed as

MetagenomeEnteric Nervous SystemEnterocolitis, NecrotizingGastrointestinal MotilityHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesIntestinal MucosaIntestinesProbioticsSepsis

Identifiers

PMID21415831
PMCPMC3155417
OpenAlexW2134253751

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.