Evidence map›Paper›PMID 21414452›Full record

Trial reportJournal of psychosomatic research2011

A pilot study of cognitive behavioral stress management effects on stress, quality of life, and symptoms in persons with chronic fatigue syndrome.

Corina Lopez, Michael Antoni, Frank Penedo, Donna Weiss, Stacy Cruess, Mary-Catherine Segotas, Lynn Helder, Scott Siegel, Nancy Klimas, Mary Ann Fletcher

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of psychosomatic research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06626061 (Promotion of Mental Health and Prevention of Burnout Among Caregivers at CHU Grenoble Alpes), which is not on this map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06626061 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Promotion of Mental Health and Prevention of Burnout Among Caregivers at CHU Grenoble Alpes (CHUGA) and CH Métropole Savoie (CHMS) Through a Stress Management Intervention Based on Cognitive Behavioral Therapies.

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2025 to 2026Enrolled240ConditionsBurnout, CaregiverArmsCognitive Behavioral Stress management in in person group Format, Cognitive Behavioral Stress management Hybrid Format
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
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  4. Trial
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  7. Review
  8. Article
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  15. Article
  16. Management of chronic fatigue syndrome/myalgic encephalomyelitis in a pediatric population: A scoping review.Journal of child health care : for professionals working with children in the hospital and community · 2020
    Article
  17. Article
  18. Article
  19. The association of major life events with chronic fatigue.Journal of psychosomatic research · 2019
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Corina LopezUniversity of Miami, Miami, FL, USA.
Michael Antoni
Frank Penedo
Donna Weiss
Stacy Cruess
Mary-Catherine Segotas
Lynn Helder
Scott Siegel
Nancy Klimas
Mary Ann Fletcher
University of Miami · US

Funding

Patient-Partner Stress Management Effects on CFS Symptoms and Neuroimmune ProcessR01NS072599 · NINDS · UNIVERSITY OF MIAMI CORAL GABLES · PI ANTONI, MICHAEL HOWARD · 2010 to 2014
$2.7M
Cognitive Behavioral Stress Management for Chronic Fatigue SyndromeR01NS055672 · NINDS · UNIVERSITY OF MIAMI CORAL GABLES · PI ANTONI, MICHAEL HOWARD · 2006 to 2009
$1.3M
MECHANISMS OF BLOOD VOLUME ABNORMALITIES IN CFSU01AI045940 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI KLIMAS, NANCY GRACE · 1999 to 2002
$1.1M
NIAID NIH HHS 1 U01 AI45940NIAID NIH HHS U01 AI045940NINDS NIH HHS 1R01 NS055672-01NINDS NIH HHS R01 NS055672NINDS NIH HHS R01 NS072599
6 · The paper itself

Abstract

objectiveThe present pilot study was designed to test the effects of a 12-week group-based cognitive behavioral stress management (CBSM) intervention on stress, quality of life, and symptoms in chronic fatigue syndrome (CFS). We hypothesized that participants randomized to CBSM would report improvements in perceived stress, mood, quality of life, and CFS symptomatology from pre- to postintervention compared to those receiving a psychoeducational (PE) seminar control.

methodWe recruited 69 persons with a bona fide diagnosis of CFS and randomized 44 to CBSM and 25 to PE. Participants completed the Perceived Stress Scale (PSS), Profile of Mood States (POMS), Quality of Life Inventory (QOLI), and a Centers for Disease Control (CDC)-based CFS symptom checklist pre- and postintervention.

resultsRepeated measures analysis of variance revealed a significant Group×Time interaction for PSS, POMS-total mood disturbance (TMD), and QOLI scores, such that participants in CBSM evidenced greater improvements than those in PE. Participants in CBSM also reported decreases in severity of CFS symptoms vs. those in PE.

conclusionsResults suggest that CBSM is beneficial for managing distress, improving quality of life, and alleviating CFS symptom severity.

Indexed as

Cognitive Behavioral TherapyAdultAnalysis of VarianceDepressionFatigue Syndrome, ChronicFemaleHumansMaleMiddle AgedPatient Education as TopicPilot ProjectsQuality of LifeSeverity of Illness IndexStress, PsychologicalTreatment Outcome

Identifiers

PMID21414452
PMCPMC3073706
OpenAlexW2070618700

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.