Evidence map›Paper›PMID 21414419›Full record

ReviewDrug discovery today2011

Design and engineering of nanogels for cancer treatment.

Murali Mohan Yallapu, Meena Jaggi, Subhash C Chauhan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Drug discovery today, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
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  14. Article
  15. Uniquely sized nanogelsRSC advances · 2022
    Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Gambogic acid: A shining natural compound to nanomedicine for cancer therapeutics.Biochimica et biophysica acta. Reviews on cancer · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Murali Mohan YallapuCancer Biology Research Center, Sanford Research/University of South Dakota, Sioux Falls, SD 57104, USA.
Meena Jaggi
Subhash C Chauhan

Funding

Aspects of MUC13 Mucin in CancerR01CA142736 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI CHAUHAN, SUBHASH C. · 2010 to 2013
$1.2M
NCI NIH HHS R01 CA142736
6 · The paper itself

Abstract

Here, we provide a comprehensive insight into current advances in the use of nanogel-mediated chemotherapy for cancer treatment. Nanogels are composed of cross-linked three-dimensional polymer chain networks that are formed via covalent linkages or self-assembly processes. The porosity between the cross-linked networks of nanogels not only provides an ideal reservoir for loading drugs, oligonucleotides and imaging agents, but also protects them from environmental degradation and hazards. Here, we focus mainly on novel synthetic strategies and key considerations in the design of nanogel-based drug delivery systems for controlled and targeted cancer therapeutic applications.

Indexed as

Drug DesignAntineoplastic AgentsDrug Delivery SystemsHumansNanogelsNeoplasmsPolyethylene GlycolsPolyethyleneimineAntineoplastic AgentsNanogelspolyethylene glycol polyethyleneimine nanogelPolyethylene GlycolsPolyethyleneimine

Identifiers

PMID21414419
PMCPMC3095726

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.