ReviewHearing research2011
Potassium channel modulation and auditory processing.
Review in Hearing research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 42 citations in OpenAlex.
- Learning induces unique transcriptional landscapes in the auditory cortex.Hearing research · 2023Review
- Learning induces unique transcriptional landscapes in the auditory cortex.bioRxiv : the preprint server for biology · 2023Article
- Hyperacusis in the AdultInternational journal of molecular sciences · 2023Article
- Axonal and presynaptic FMRP: Localization, signal, and functional implications.Hearing research · 2023Review
- Double-edged Role of KCurrent neuropharmacology · 2022Review
- Absence of the Fragile X messenger ribonucleoprotein alters response patterns to sounds in the auditory midbrain.Frontiers in neuroscience · 2022Article
- Expression and Localization of Kv1.1 and Kv3.1b Potassium Channels in the Cochlear Nucleus and Inferior Colliculus after Long-Term Auditory Deafferentation.Brain sciences · 2020Article
- Functional Development of Principal Neurons in the Anteroventral Cochlear Nucleus Extends Beyond Hearing Onset.Frontiers in cellular neuroscience · 2019Article
- Postsynaptic FMRP Regulates SynaptogenesisThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Kv3 Channels: Enablers of Rapid Firing, Neurotransmitter Release, and Neuronal Endurance.Physiological reviews · 2017Review
- Ion channel mechanisms underlying frequency-firing patterns of the avian nucleus magnocellularis: A computational model.Channels (Austin, Tex.) · 2017Article
- Enhanced Excitatory Connectivity and Disturbed Sound Processing in the Auditory Brainstem of Fragile X Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- The need for new approaches in CNS drug discovery: Why drugs have failed, and what can be done to improve outcomes.Neuropharmacology · 2017Review
- Cellular distribution of the fragile X mental retardation protein in the mouse brain.The Journal of comparative neurology · 2017Article
- Article
- Fragile X mental retardation protein controls ion channel expression and activity.The Journal of physiology · 2016Review
- Intrinsic plasticity induced by group II metabotropic glutamate receptors via enhancement of high-threshold KV currents in sound localizing neurons.Neuroscience · 2016Article
- In vivo Whole-Cell Recordings Combined with Electron Microscopy Reveal Unexpected Morphological and Physiological Properties in the Lateral Nucleus of the Trapezoid Body in the Auditory Brainstem.Frontiers in neural circuits · 2016Article
- Transcriptional maturation of the mouse auditory forebrain.BMC genomics · 2015Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
For accurate processing of auditory information, neurons in auditory brainstem nuclei have to fire at high rates with high temporal accuracy. These two requirements can only be fulfilled when the intrinsic electrical properties of these neurons are matched to the pattern of incoming synaptic stimulation. This review article focuses on three families of potassium channels that are critical to shaping the firing pattern and accuracy of neurons. Changes in the auditory environment can trigger very rapid changes in the phosphorylation state of potassium channels in auditory brainstem nuclei. Longer lasting changes in the auditory environment produce changes in the rates of translation and transcription of genes encoding these channels. A key protein that plays a role in setting the overall sensitivity of the auditory system to sound stimuli is FMRP (Fragile X Mental Retardation Protein), which binds channels directly and also regulates the translation of mRNAs for the channels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.