Evidence map›Paper›PMID 21414009›Full record

ArticleVox sanguinis2011

An association of ABO non-identical platelet and cryoprecipitate transfusions with altered red cell transfusion needs in surgical patients.

Majed A Refaai, Lawrence B Fialkow, Joanna M Heal, Kelly F Henrichs, Sherry L Spinelli, Richard P Phipps, Edward Masel, Brian H Smith, James P Corsetti, Charles W Francis and 2 more

Open access · greenAbstract readComparative Study
In one paragraph

Article in Vox sanguinis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
  2. The Evolution of Blood Product Use in Trauma Resuscitation: Change Has Come.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2021
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. ABO mismatched platelet transfusions in trauma patients.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2014
    Article
  11. Platelet transfusion - the art and science of compromise.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2013
    Article
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Majed A RefaaiDepartment of Pathology and Laboratory Medicine, University of Rochester, Rochester, NY, USA.
Lawrence B Fialkow
Joanna M Heal
Kelly F Henrichs
Sherry L Spinelli
Richard P Phipps
Edward Masel
Brian H Smith
James P Corsetti
Charles W Francis
Paul E Bankey
Neil Blumberg
University of Rochester · US

Funding

Identification and Significance of Biologic Mediators in Red Cell ConcentratesR01HL095467 · NHLBI · UNIVERSITY OF ROCHESTER · PI BLUMBERG, NEIL, PHIPPS, RICHARD P. · 2009 to 2012
$1.5M
Platelet Activation and Inflammatory MediatorsR01HL078603 · NHLBI · UNIVERSITY OF ROCHESTER · PI PHIPPS, RICHARD P. · 2004 to 2007
$1.2M
Microparticles as Messengers of Communication Between Blood and Vascular CellsRC1HL100051 · NHLBI · UNIVERSITY OF ROCHESTER · PI PHIPPS, RICHARD P. · 2009 to 2010
$1.0M
Blood Transfusions: Gender Differences in Utilization, Predictors, and OutcomesR21HL093129 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ROGERS, MARY A. M. · 2009 to 2010
$438k
Normal and Type-2 Diabetic Platelet Proteomics StorageR21HL086367 · NHLBI · UNIVERSITY OF ROCHESTER · PI PHIPPS, RICHARD P. · 2006 to 2007
$426k
NHLBI NIH HHS HL078603NHLBI NIH HHS HL086367NHLBI NIH HHS HL093129NHLBI NIH HHS HL095467NHLBI NIH HHS HL100051NHLBI NIH HHS R01 HL078603NHLBI NIH HHS R01 HL095467NHLBI NIH HHS R21 HL086367NHLBI NIH HHS R21 HL093129NHLBI NIH HHS RC1 HL100051
6 · The paper itself

Abstract

backgroundTransfusion of ABO non-identical plasma, platelets and cryoprecipitate is routine practice even though adverse effects can occur. METHODS AND MATERIALS: Our hospital changed transfusion practice in 2005 and adopted a policy of providing ABO-identical blood components to all patients when feasible. We retrospectively compared the transfusion requirements, length of stay and in-hospital mortality in relation to ABO blood group in surgical patients who received platelet transfusions before and after this change to determine whether it resulted in any benefit.

resultsPrior to the change in practice, both group B and AB patients received more ABO non-identical platelet transfusion (P=0·0004), required significantly greater numbers of red cell transfusions (P=0·04) and had 50% longer hospital stays (P=0·039) than group O and A patients. Following the policy change, there was a trend for fewer red cell transfusions (P=0·17) and length of stay in group B and AB patients than group O or A patients. Overall, the mortality rate per red cell transfusion decreased from 15·2 per 1000 to 11·0 per 1000 (P=0·013).

conclusionsThese results, in the context of previous findings, suggest that providing ABO-identical platelets and cryoprecipitate might be associated with reduction in transfusion requirements and improve outcomes in surgical patients.

Indexed as

Hospital MortalityABO Blood-Group SystemAdultAgedBlood Component TransfusionBlood Group IncompatibilityBlood Grouping and CrossmatchingErythrocyte TransfusionFemaleHumansLength of StayMaleMiddle AgedPlasmaPlatelet TransfusionPostoperative HemorrhageABO Blood-Group System

Identifiers

PMID21414009
PMCPMC3115402
OpenAlexW1949217653

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.