Evidence map›Paper›PMID 21412865›Full record

SynthesisThe Cochrane database of systematic reviews2011

Dietary sodium manipulation and asthma.

Zara Pogson, Tricia McKeever

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Interventions for managing asthma in pregnancy.The Cochrane database of systematic reviews · 2014
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Evidence for lifestyle interventions in asthma.Breathe (Sheffield, England) · 2019
    Review
  9. Review
  10. Review
  11. Association between Western diet pattern and adult asthma: a focused review.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2015
    Review
  12. Sodium intake is associated with increased disease activity in multiple sclerosis.Journal of neurology, neurosurgery, and psychiatry · 2015
    Observational
  13. Cardiovascular and other effects of salt consumption.Kidney international supplements · 2013
    Article
  14. Review
  15. Practical approach to exercise-induced bronchoconstriction in athletes.Primary care respiratory journal : journal of the General Practice Airways Group · 2013
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Zara PogsonRespiratory Medicine, Sherwood Forest NHS Trust, Kings Mills Hospital, Sutton in Ashfield, Nottinghamshire, UK, NG17 4JL.
Tricia McKeever
Kings Mill Hospital · GBNottingham City Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a wide geographical variation in the prevalence of asthma and observational studies have suggested that dietary sodium may play a role.

objectivesTo assess the effect of dietary sodium manipulation on asthma control. SEARCH STRATEGY: We carried out a search using the Cochrane Airways Group asthma register. We searched the bibliographies of included randomised controlled trials (RCTs) for additional studies. We carried out the most recent search in November 2010. SELECTION CRITERIA: We considered only RCTs that involved dietary sodium reduction or increased sodium intake in patients with asthma. DATA COLLECTION AND ANALYSIS: Both review authors assessed study and extracted data. We conducted data analyses in RevMan 5 using mean differences and random effects. MAIN

resultsWe identified a total of nine studies in relation to sodium manipulation and asthma, of which five were in people with asthma (318 participants), and four in people with exercise-induced asthma (63 participants). There were no significant benefits of salt restriction on the control of asthma. There was some evidence from the exercise-induced asthma studies that a low sodium diet may improve lung function after exercise and possibly baseline lung function, but this is based on findings from a very small numbers of participants. AUTHORS'

conclusionsThis review did not find any evidence that dietary sodium reduction significantly improves asthma control. Although dietary sodium reduction may result in improvements in lung function in exercise-induced asthma, the clinical significance of this effect is unclear.

Indexed as

Diet, Sodium-RestrictedAsthmaAsthma, Exercise-InducedHumansRandomized Controlled Trials as TopicSodium Chloride, DietarySodium Chloride, Dietary

Identifiers

PMID21412865
PMCPMC7032646
OpenAlexW1581309011

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.