Evidence map›Paper›PMID 21412774›Full record

ReviewJournal of cellular physiology2012

MicroRNAs: Allies or foes in erythropoiesis?

John C H Byon, Thalia Papayannopoulou

Abstract readReview
In one paragraph

Review in Journal of cellular physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  17. Article
  18. MicroRNAs in myeloproliferative neoplasms.British journal of haematology · 2013
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John C H ByonDivision of Hematology, Department of Medicine, University of Washington, Seattle, Washington, USA.
Thalia Papayannopoulou

Funding

Career Development in Clinical Hematology ResearchK12HL087165 · NHLBI · UNIVERSITY OF WASHINGTON · PI ABKOWITZ, JANIS L · 2006 to 2016
$4.0M
BIOLOGICAL PROPERTIES AND REGULATION OF STEM CELLSR01HL046557 · NHLBI · UNIVERSITY OF WASHINGTON · PI STAMATOYANNOPOULOS, THALIA · 1991 to 2009
$3.3M
Homing Determinants in Hemopoietic Stem/Progenitor CellsR01HL058734 · NHLBI · UNIVERSITY OF WASHINGTON · PI STAMATOYANNOPOULOS, THALIA · 1997 to 2011
$3.2M
NHLBI NIH HHS HL058734NHLBI NIH HHS HL46557NHLBI NIH HHS K12 HL087165NHLBI NIH HHS K12HL087165NHLBI NIH HHS R01 HL046557NHLBI NIH HHS R01 HL058734
6 · The paper itself

Abstract

MicroRNAs are small non-coding RNAs that negatively regulate gene expression through mRNA degradation or translational repression. It is becoming increasingly recognized that miRNAs play central roles in almost all cellular processes, and especially during development. The function of miRNAs in hematopoiesis, including erythropoiesis, is beginning to be elucidated. In this review, we will focus on what is known about miRNA function in various aspects of erythropoiesis and red cell physiology.

Indexed as

AnimalsErythropoiesisGene Expression RegulationHumansMicroRNAsMicroRNAs

Identifiers

PMID21412774
PMCPMC3128660

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.