Evidence map›Paper›PMID 21411585›Full record

ArticleJournal of clinical microbiology2011

Aptima Combo 2 testing detected additional cases of Neisseria gonorrhoeae infection in men and women in community settings.

Julius Kapala, Kathy Biers, Michael Cox, Margaret Kamionka, Jeff Sumner, Ramandeep Toor, Jodi Gilchrist, Dan Jang, Marek Smieja, Max Chernesky

Open access · greenAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Management of gonococcal infection among adults and youth: New key recommendations.Canadian family physician Medecin de famille canadien · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Julius KapalaGamma Dynacare Medical Laboratories, Brampton, Ontario, Canada.
Kathy Biers
Michael Cox
Margaret Kamionka
Jeff Sumner
Ramandeep Toor
Jodi Gilchrist
Dan Jang
Marek Smieja
Max Chernesky
McMaster University · CASt. Joseph’s Healthcare Hamilton · CABrampton Civic Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aptima Combo 2 (AC2) Neisseria gonorrhoeae testing of 81,405 patients who were tested by culture and 14,666 who were AC2 tested for Chlamydia trachomatis detected 142 extra infections and confirmed 106 culture-positive samples (the positivity rate increased from 0.13 in testing by culture to 0.26 in testing by AC2). Retrievable AC2 positive samples were confirmed (98.5%) by an alternate AGC test.

Indexed as

Chlamydia InfectionsChlamydia trachomatisFemaleGonorrheaHumansMaleMolecular Diagnostic TechniquesNeisseria gonorrhoeaeNucleic Acid Amplification TechniquesSensitivity and Specificity

Identifiers

PMID21411585
PMCPMC3122629
OpenAlexW2158293168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.