Evidence map›Paper›PMID 21410958›Full record

ArticleBMC gastroenterology2011

Safety of pull-type and introducer percutaneous endoscopic gastrostomy tubes in oncology patients: a retrospective analysis.

Evi Van Dyck, Elisabeth J Macken, Bernard Roth, Paul A Pelckmans, Tom G Moreels

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03252509 (Outpatient Percutaneous Radiologic Gastrostomy in Patients With Head and Neck Tumors), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03252509 nacompletednot on this mapstarted 2017, after this paper: background citation

Outpatient Percutaneous Radiologic Gastrostomy in Patients With Head and Neck Tumors

TypeinterventionalSponsorInstituto Nacional de Cancer, BrazilRan2017 to 2018Enrolled39ConditionsGastrostomy, Head and Neck Neoplasms, Malignant NeoplasmArmsPercutaneous radiologic gastrostomy
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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  6. [Clinical Practice Guideline for Percutaneous Endoscopic Gastrostomy].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Evi Van DyckAntwerp University Hospital, Wilrijkstraat 10, B-2650 Antwerp, Belgium.
Elisabeth J Macken
Bernard Roth
Paul A Pelckmans
Tom G Moreels
Antwerp University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous endoscopic gastrostomy (PEG) allows long-term tube feeding. Safety of pull-type and introducer PEG placement in oncology patients with head/neck or oesophageal malignancies is unknown.

methodsRetrospective analysis of 299 patients undergoing PEG tube placement between January 2006 and December 2008 revealed 57 oncology patients. All patients with head/neck or oesophageal malignancy were treated with chemo- and radiotherapy. In case of high-grade stenosis introducer Freka® Pexact PEG tube was placed (n = 24) and in all other patients (n = 33) conventional pull-type PEG tube. Short-term complications and mortality rates were compared.

resultsPatients' characteristics and clinical status were comparable in both groups. Short-term complications were encountered in 11/24 (48%) introducer PEG patients as compared to only 4/33 (12%) pull-type PEG patients (P < 0.05). Accidental removal of the introducer PEG tube occurred in 4/24 (17%) with need for surgical intervention in 1 vs. 0/33 (0%, P < 0.05). Wound infection occurred in 3/24 (12%) leading to septic shock and admission to intensive care unit (ICU) in 1 vs. 3/33 (9%, NS). Finally, 3/24 gastrointestinal perforations (12%) resulted from a difficult placement procedure vs. 1/33 (3%), leading to urgent surgical intervention and admission to ICU. Two introducer PEG patients died at ICU, resulting in an overall mortality rate of 8% vs. 0% (P = 0.091).

conclusionThe introducer Freka® Pexact PEG procedure for long-term tube feeding may lead to significantly higher complication and mortality rates in patients with head/neck or oesophageal malignancies treated with chemo- and radiotherapy. It is suggested to use the conventional pull-type PEG tube placement in this group of patients, if possible.

Indexed as

AgedEndoscopy, GastrointestinalEnteral NutritionEsophageal NeoplasmsFemaleGastrostomyHead and Neck NeoplasmsHumansMaleMiddle AgedPostoperative ComplicationsPrevalenceRetrospective StudiesSurvival Rate

Identifiers

PMID21410958
PMCPMC3068968
OpenAlexW2047688333

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.