ArticleNeuroinformatics2011
Inverse current source density method in two dimensions: inferring neural activation from multielectrode recordings.
Article in Neuroinformatics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Wave propagation enhances extracellular signal strength in small excitable tissues.Scientific reports · 2026Article
- kCSD-python, reliable current source density estimation with quality control.PLoS computational biology · 2024Article
- Article
- Discovering optimal features for neuron-type identification from extracellular recordings.Frontiers in neuroinformatics · 2024Article
- A physical neural mass model framework for the analysis of oscillatory generators from laminar electrophysiological recordings.NeuroImage · 2023Article
- Recording Saltatory Conduction Along Sensory Axons Using a High-Density Microelectrode Array.Frontiers in neuroscience · 2022Article
- Cross-population coupling of neural activity based on Gaussian process current source densities.PLoS computational biology · 2021Article
- Gamma Oscillations in the Basolateral Amygdala: Localization, Microcircuitry, and Behavioral Correlates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- What we can and what we cannot see with extracellular multielectrodes.PLoS computational biology · 2021Article
- waveCSD: A method for estimating transmembrane currents originated from propagating neuronal activity in the neocortex: Application to study cortical spreading depression.Journal of neuroscience methods · 2018Article
- Multimodal Modeling of Neural Network Activity: Computing LFP, ECoG, EEG, and MEG Signals With LFPy 2.0.Frontiers in neuroinformatics · 2018Article
- Differential recordings of local field potential: A genuine tool to quantify functional connectivity.PloS one · 2018Article
- Article
- Focal Local Field Potential Signature of the Single-Axon Monosynaptic Thalamocortical Connection.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- From Maxwell's equations to the theory of current-source density analysis.The European journal of neuroscience · 2017Article
- Linear distributed source modeling of local field potentials recorded with intra-cortical electrode arrays.PloS one · 2017Article
- Collection of Simulated Data from a Thalamocortical Network Model.Neuroinformatics · 2017Article
- Effect of Ionic Diffusion on Extracellular Potentials in Neural Tissue.PLoS computational biology · 2016Article
- Spatial spread of local field potential is band-pass in the primary visual cortex.Journal of neurophysiology · 2016Article
- Generalized Laminar Population Analysis (gLPA) for Interpretation of Multielectrode Data from Cortex.Frontiers in neuroinformatics · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The recent development of large multielectrode recording arrays has made it affordable for an increasing number of laboratories to record from multiple brain regions simultaneously. The development of analytical tools for array data, however, lags behind these technological advances in hardware. In this paper, we present a method based on forward modeling for estimating current source density from electrophysiological signals recorded on a two-dimensional grid using multi-electrode rectangular arrays. This new method, which we call two-dimensional inverse Current Source Density (iCSD 2D), is based upon and extends our previous one- and three-dimensional techniques. We test several variants of our method, both on surrogate data generated from a collection of Gaussian sources, and on model data from a population of layer 5 neocortical pyramidal neurons. We also apply the method to experimental data from the rat subiculum. The main advantages of the proposed method are the explicit specification of its assumptions, the possibility to include system-specific information as it becomes available, the ability to estimate CSD at the grid boundaries, and lower reconstruction errors when compared to the traditional approach. These features make iCSD 2D a substantial improvement over the approaches used so far and a powerful new tool for the analysis of multielectrode array data. We also provide a free GUI-based MATLAB toolbox to analyze and visualize our test data as well as user datasets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.