ArticlePloS one2011
Mutant analysis in Arabidopsis provides insight into the molecular mode of action of the auxinic herbicide dicamba.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 87 citations in OpenAlex.
- Quantitative trait loci analysis identifying novel genomic regions for off-target dicamba tolerance in soybean [Glycine max (L.) Merr.].BMC plant biology · 2026Article
- Can the right partner mitigate harm? Rhizobial strains vary in their mediation of herbicide stress in a plant-rhizobia mutualism.Evolution letters · 2026Article
- A deletion upstream of the degron of AcIAA27 leads to auxinic herbicide resistance in Arctotheca calendula.Pest management science · 2025Article
- A point mutation in IAA34 confers resistance to the auxin herbicide 2,4-D in Sisymbrium orientale.Pest management science · 2025Article
- A transposable element insertion in AUX/IAA16 disrupts splicing and causes auxin resistance in Bassia scoparia.The Plant journal : for cell and molecular biology · 2025Article
- Rhizobial variation, more than plant variation, mediates plant symbiotic and fitness responses to herbicide stress.Ecology · 2024Article
- Article
- Detection and differentiation of herbicide stresses in roses by Raman spectroscopy.Frontiers in plant science · 2023Article
- Article
- TIR1/AFB proteins: Active players in abiotic and biotic stress signaling.Frontiers in plant science · 2022Review
- A Common Feature of Pesticides: Oxidative Stress-The Role of Oxidative Stress in Pesticide-Induced Toxicity.Oxidative medicine and cellular longevity · 2022Review
- A network of stress-related genes regulates hypocotyl elongation downstream of selective auxin perception.Plant physiology · 2021Article
- Two Auxinic Herbicides AffectBiomolecules · 2021Article
- The chemical compound 'Heatin' stimulates hypocotyl elongation and interferes with the Arabidopsis NIT1-subfamily of nitrilases.The Plant journal : for cell and molecular biology · 2021Article
- Evaluation of a Stable Isotope-Based Direct Quantification Method for Dicamba Analysis from Air and Water Using Single-Quadrupole LC-MS.Molecules (Basel, Switzerland) · 2020Article
- Transcriptomics in Erigeron canadensis reveals rapid photosynthetic and hormonal responses to auxin herbicide application.Journal of experimental botany · 2020Article
- Investigation of physiological and molecular mechanisms conferring diurnal variation in auxinic herbicide efficacy.PloS one · 2020Article
- Plant growth-promoting activity of beta-propeller protein YxaL secreted from Bacillus velezensis strain GH1-13.PloS one · 2019Article
- Plant reproduction is altered by simulated herbicide drift to constructed plant communities.Environmental toxicology and chemistry · 2017Article
- Unraveling plant hormone signaling through the use of small molecules.Frontiers in plant science · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herbicides that mimic the natural auxin indole-3-acetic acid are widely used in weed control. One common auxin-like herbicide is dicamba, but despite its wide use, plant gene responses to dicamba have never been extensively studied. To further understand dicamba's mode of action, we utilized Arabidopsis auxin-insensitive mutants and compared their sensitivity to dicamba and the widely-studied auxinic herbicide 2,4-dichlorophenoxyacetic acid (2,4-D). The mutant axr4-2, which has disrupted auxin transport into cells, was resistant to 2,4-D but susceptible to dicamba. By comparing dicamba resistance in auxin signalling F-box receptor mutants (tir1-1, afb1, afb2, afb3, and afb5), only tir1-1 and afb5 were resistant to dicamba, and this resistance was additive in the double tir1-1/afb5 mutant. Interestingly, tir1-1 but not afb5 was resistant to 2,4-D. Whole genome analysis of dicamba-induced gene expression showed that 10 hours after application, dicamba stimulated many stress-responsive and signalling genes, including those involved in biosynthesis or signalling of auxin, ethylene, and abscisic acid (ABA), with TIR1 and AFB5 required for the dicamba-responsiveness of some genes. Research into dicamba-regulated gene expression and the selectivity of auxin receptors has provided molecular insight into dicamba-regulated signalling and could help in the development of novel herbicide resistance in crop plants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.