Evidence map›Paper›PMID 21408060›Full record

Trial reportPloS one2011

On-line randomized controlled trial of an internet based psychologically enhanced intervention for people with hazardous alcohol consumption.

Paul Wallace, Elizabeth Murray, Jim McCambridge, Zarnie Khadjesari, Ian R White, Simon G Thompson, Eleftheria Kalaitzaki, Christine Godfrey, Stuart Linke

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  6. Behavior Change Techniques Used in Digital Behavior Change Interventions to Reduce Excessive Alcohol Consumption: A Meta-regression.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2018
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  10. Internet-based randomized controlled trials: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paul WallaceE-health Unit, Research Department of Primary Care and Population Health, University College London, London, United Kingdom. p.wallace@ucl.ac.uk
Elizabeth Murray
Jim McCambridge
Zarnie Khadjesari
Ian R White
Simon G Thompson
Eleftheria Kalaitzaki
Christine Godfrey
Stuart Linke

Funding

British Heart Foundation RG/08/014/24067Cancer Research UKChief Scientist OfficeDepartment of HealthMedical Research Council G0501298Medical Research Council MC_U105260558Medical Research Council MC_U105260792Medical Research Council MC_U122797163Medical Research Council U.1052.00.001Medical Research Council U.1052.00.006
6 · The paper itself

Abstract

backgroundInterventions delivered via the Internet have the potential to address the problem of hazardous alcohol consumption at minimal incremental cost, with potentially major public health implications. It was hypothesised that providing access to a psychologically enhanced website would result in greater reductions in drinking and related problems than giving access to a typical alcohol website simply providing information on potential harms of alcohol. DYD-RCT Trial registration: ISRCTN 31070347. METHODOLOGY/PRINCIPAL

findingsA two-arm randomised controlled trial was conducted entirely on-line through the Down Your Drink (DYD) website. A total of 7935 individuals who screened positive for hazardous alcohol consumption were recruited and randomized. At entry to the trial, the geometric mean reported past week alcohol consumption was 46.0 (SD 31.2) units. Consumption levels reduced substantially in both groups at the principal 3 month assessment point to an average of 26.0 (SD 22.3) units. Similar changes were reported at 1 month and 12 months. There were no significant differences between the groups for either alcohol consumption at 3 months (intervention: control ratio of geometric means 1.03, 95% CI 0.97 to 1.10) or for this outcome and the main secondary outcomes at any of the assessments. The results were not materially changed following imputation of missing values, nor was there any evidence that the impact of the intervention varied with baseline measures or level of exposure to the intervention. CONCLUSIONS/SIGNIFICANCE: Findings did not provide support for the hypothesis that access to a psychologically enhanced website confers additional benefit over standard practice and indicate the need for further research to optimise the effectiveness of Internet-based behavioural interventions. The trial demonstrates a widespread and potentially sustainable demand for Internet based interventions for people with hazardous alcohol consumption, which could be delivered internationally.

trial registrationControlled-Trials.com ISRCTN31070347.

Indexed as

InternetAlcohol DrinkingFollow-Up StudiesHumansPatient SelectionTreatment Outcome

Identifiers

PMID21408060
PMCPMC3052303

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.