Evidence map›Paper›PMID 21406678›Full record

ReviewCirculation. Heart failure2011

Reverse remodeling with left ventricular assist devices: a review of clinical, cellular, and molecular effects.

Amrut V Ambardekar, Peter M Buttrick

Abstract readReview
In one paragraph

Review in Circulation. Heart failure, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Update of the Brazilian Guideline on Nuclear Cardiology - 2020.Arquivos brasileiros de cardiologia · 2020
    Guideline
  3. Trial
  4. Trial
  5. Molecular Mechanisms of Cardiac Adaptation After Device Deployment.Journal of cardiovascular development and disease · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. The Diabetic Cardiorenal Nexus.International journal of molecular sciences · 2022
    Review
  11. Review
  12. Review
  13. Review
  14. Pathophysiology of sepsis-induced cardiomyopathy.Nature reviews. Cardiology · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amrut V AmbardekarDivision of Cardiology, University of Colorado Denver, Aurora, CO 80045, USA. Amrut.Ambardekar@ucdenver.edu
Peter M Buttrick

Funding

Myofilament Function in Human Heart FailureR01HL077195 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BUTTRICK, PETER N. · 2005 to 2008
$1.8M
Using Molecular Pathology to Predict Response in Heart FailureP20HL101435 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BUTTRICK, PETER N., LOWES, BRIAN D · 2010 to 2011
$1.5M
NHLBI NIH HHS HL077195NHLBI NIH HHS HL101435NHLBI NIH HHS P20 HL101435NHLBI NIH HHS R01 HL077195
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Heart-Assist DevicesVentricular Function, LeftVentricular RemodelingCalciumCytokinesExtracellular Matrix ProteinsGene Expression RegulationHeart FailureHeart VentriclesHumansMyocardial ContractionNatriuretic PeptidesNeurotransmitter AgentsProsthesis DesignReceptors, Adrenergic, betaRecovery of FunctionCalciumCytokinesExtracellular Matrix ProteinsNatriuretic PeptidesNeurotransmitter AgentsReceptors, Adrenergic, beta

Identifiers

PMID21406678
PMCPMC3385856

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.