Evidence map›Paper›PMID 21406084›Full record

ArticleParticle and fibre toxicology2011

The procoagulant effects of fine particulate matter in vivo.

Evren Kilinç, Holger Schulz, Gerhardus Jajm Kuiper, Henri Mh Spronk, Hugo Ten Cate, Swapna Upadhyay, Koustav Ganguly, Tobias Stoeger, Manuela Semmler-Bhenke, Shinji Takenaka and 6 more

Open access · goldAbstract readCommentLetter
In one paragraph

Article in Particle and fibre toxicology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Evren Kilinç
Holger Schulz
Gerhardus Jajm Kuiper
Henri Mh Spronk
Hugo Ten Cate
Swapna Upadhyay
Koustav Ganguly
Tobias Stoeger
Manuela Semmler-Bhenke
Shinji Takenaka
Wolfgang G Kreyling
Mike Pitz
Peter Reitmeir
Annette Peters
Oliver Eickelberg
H Erich Wichmann
Helmholtz Zentrum München · DEUniversity Medical Center · USUniversity of Pittsburgh · USMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhalation of fine particulate matter (<2.5 μm; fine PM) has been shown to increase the risk for cardiovascular events. In this letter, we reappraise the role of tissue factor (TF) antigen and we also summarize changes in measured coagulation proteins in humans and rodents by other studies with fine PM. By considering all studies including ours, we conclude that monitoring the overall coagulation state by measuring capacity assays such as thrombin generation, and quantification of TF activity would be more suitable than determining single coagulation proteins (such as TF antigen) in order to better assess the systemic prothrombotic effects of fine PM.

Indexed as

AnimalsBiomarkersBlood CoagulationHumansInhalation ExposureParticle SizeParticulate MatterThrombinThromboplastinBiomarkersParticulate MatterThrombinThromboplastin

Identifiers

PMID21406084
PMCPMC3068090
OpenAlexW2111800037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.