ArticleParkinson's disease2011
Impulse control disorders following deep brain stimulation of the subthalamic nucleus in Parkinson's disease: clinical aspects.
Article in Parkinson's disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 67 citations in OpenAlex.
- Morphometric alterations of the mesocorticolimbic network in Parkinson's disease with impulse control disorders.Journal of neural transmission (Vienna, Austria : 1996) · 2024Article
- Measures of impulsivity in Parkinson's disease decrease after DBS in the setting of stable dopamine therapy.Parkinsonism & related disorders · 2017Observational
- Impulse Control Disorders and Related Complications of Parkinson's Disease Therapy.Seminars in neurology · 2017Review
- Earlier Intervention with Deep Brain Stimulation for Parkinson's Disease.Parkinson's disease · 2017Review
- Pathological gambling in Parkinson's disease: what are the risk factors and what is the role of impulsivity?The European journal of neuroscience · 2017Review
- The effect of deep brain stimulation on the non-motor symptoms of Parkinson's disease: a critical review of the current evidence.NPJ Parkinson's disease · 2017Review
- The Subthalamic Nucleus, Limbic Function, and Impulse Control.Neuropsychology review · 2015Review
- The treatment of Parkinson's disease with deep brain stimulation: current issues.Neural regeneration research · 2015Review
- In a rush to decide: deep brain stimulation and dopamine agonist therapy in Parkinson's disease.Journal of Parkinson's disease · 2014Article
- Should impulse control disorders and dopamine dysregulation syndrome be indications for deep brain stimulation and intestinal levodopa?Movement disorders : official journal of the Movement Disorder Society · 2013Review
- Deep brain stimulation in Parkinson's disease.Translational neurodegeneration · 2013Article
- Timing of deep brain stimulation in Parkinson disease: a need for reappraisal?Annals of neurology · 2013Article
- Dopamine agonists rather than deep brain stimulation cause reflection impulsivity in Parkinson's disease.Journal of Parkinson's disease · 2013Article
- Impulse control disorders in Parkinson's disease: background and update on prevention and management.Neurodegenerative disease management · 2012Article
- Dopamine agonists and pathologic behaviors.Parkinson's disease · 2012Article
- Effects of STN and GPi deep brain stimulation on impulse control disorders and dopamine dysregulation syndrome.PloS one · 2012Article
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Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parkinson's disease (PD) has been associated with the development of impulse control disorders (ICDs), possibly due to overstimulation of the mesolimbic system by dopaminergic medication. Preliminary reports have suggested that deep brain stimulation (DBS), a neurosurgical procedure offered to patients with treatment-resistant PD, affects ICD in a twofold way. Firstly, DBS allows a decrease in dopaminergic medication and hence causes an improvement in ICDs. Secondly, some studies have proposed that specific ICDs may develop after DBS. This paper addresses the effects of DBS on ICDs in patients with PD. A literature search identified four original studies examining a total of 182 patients for ICDs and nine case reports of 39 patients that underwent DBS and developed ICDs at some point. Data analysis from the original studies did not identify a significant difference in ICDs between patients receiving dopaminergic medication and patients on DBS, whilst the case reports showed that 56% of patients undergoing DBS had poor outcome with regards to ICDs. We discuss these ambivalent findings in the light of proposed pathogenetic mechanisms. Longitudinal, prospective studies with larger number of patients are required in order to fully understand the role of DBS on ICDs in patients with PD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.