ArticleJournal of osteoporosis2011
Secondary osteoporosis in patients with juvenile idiopathic arthritis.
Article in Journal of osteoporosis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed, 43 citations in OpenAlex.
- Parental fear of progression in juvenile idiopathic arthritis and type 1 diabetes.BMJ paediatrics open · 2026Article
- Novel insights into the biology of childhood arthritis- lessons learned from the synovium.Arthritis research & therapy · 2025Review
- Bone health and physical activity in adolescents with juvenile idiopathic arthritis: a cross-sectional case-control study.Pediatric rheumatology online journal · 2024Article
- Implications of Evolving Disease Classification for Drug Approval in Juvenile Idiopathic Arthritis.Paediatric drugs · 2022Article
- Radiographs and MRI of the Cervical Spine in Juvenile Idiopathic Arthritis: A Cross-Sectional Retrospective Study.Journal of clinical medicine · 2021Article
- [Juvenile rheumatoid diseases: Endoprosthetic care of destroyed hip joints].Der Orthopade · 2015Review
- Serum sclerostin in high-activity adult patients with juvenile idiopathic arthritis.Arthritis research & therapy · 2014Article
- Glucocorticoid-associated osteoporosis in chronic inflammatory diseases: epidemiology, mechanisms, diagnosis, and treatment.Current osteoporosis reports · 2014Review
- The association between lean mass and bone mineral content in the high disease activity group of adult patients with juvenile idiopathic arthritis.BMC musculoskeletal disorders · 2014Article
- Measurement of bone mineral density by dual energy X-ray absorptiometry in juvenile idiopathic arthritis.Indian journal of pediatrics · 2014Article
- A survey of steroid-related osteoporosis diagnosis, prevention and treatment practices of pediatric rheumatologists in North America.Pediatric rheumatology online journal · 2014Article
- Sexual maturation in Egyptian boys and girls with juvenile rheumatoid arthritis.Rheumatology international · 2013Article
- Bone status in adults with early-onset juvenile idiopathic arthritis following 1-year anti-TNFα therapy and discontinuation of glucocorticoids.Rheumatology international · 2013Article
- Persistent low level of osterix accelerates interleukin-6 production and impairs regeneration after tissue injury.PloS one · 2013Article
- Assessment and management of pain in juvenile idiopathic arthritis.Pain research & managementReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone disease in patients with juvenile idiopathic arthritis (JIA) is associated with focal (joint erosion and juxtaarticular osteopenia) and systemic bone loss (generalized osteopenia or reduction of bone mass density). Pathophysiology of bone loss is multifactorial and involves particularly proinflammatory cytokines and deleterious effects of glucocorticoid therapy. Clinical studies in patients with JIA indicate excessive activation of osteoclastogenesis and reduction of bone formation. Reduction of physical activity, muscle atrophy caused by high disease activity, and compulsory restriction in movements are also associated with bone loss. In patients with JIA, the disease can be complicated by growth cartilage involvement and systemic or local growth retardation. In the absence of preventive measures, fragility fractures can occur even at an early age.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.