ArticleArchives of internal medicine2011
Collaborative care of opioid-addicted patients in primary care using buprenorphine: five-year experience.
Article in Archives of internal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 169 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Controlled Trial on the Effectiveness of Immediate Versus Delayed Access to Hospital-based Addiction Services
PRimary Care Opioid Use Disorders Treatment (PROUD) Trial
Identifying Optimal Psychosocial Interventions for Patients Receiving Office-Based Buprenorphine
Enhancing Office-based Buprenorphine Treatment: An Adaptive Psychosocial Approach
Identifying Optimal Psychosocial Interventions for Patients Receiving Office-Based Buprenorphine
An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care
Who cites it
169 citing papers in PubMed, 1 synthesis or guideline pooled it, 262 citations in OpenAlex.
- Primary care models for treating opioid use disorders: What actually works? A systematic review.PloS one · 2017Pooled it
- Differences in benefits of office based opioid treatment: Secondary analyses across sub-groups in the PROUD randomized controlled implementation trial.Addiction (Abingdon, England) · 2026Trial
- Initiating Injectable Buprenorphine in People Hospitalized With Infections: A Randomized Clinical Trial.JAMA network open · 2025Trial
- The difference-making role of staff support in implementing nurse care management for opioid use disorder treatment: A configurational analysis.Journal of substance use and addiction treatment · 2025Trial
- Does implementation of office based addiction treatment by a nurse care manager increase the duration of OUD treatment in primary care? A secondary analysis of the PROUD randomized control trial.Drug and alcohol dependence · 2024Trial
- Nurse Care Management of Opioid Use Disorder Treatment After 3 Years: A Secondary Analysis of the PROUD Cluster Randomized Clinical Trial.JAMA network open · 2024Trial
- Offering nurse care management for opioid use disorder in primary care: Impact on emergency and hospital utilization in a cluster-randomized implementation trial.Drug and alcohol dependence · 2024Trial
- Methamphetamine use and illicit opioid use during buprenorphine treatment.Journal of substance use and addiction treatment · 2023Trial
- The Emergency Department Longitudinal Integrated Care (ED-LINC) intervention targeting opioid use disorder: A pilot randomized clinical trial.Journal of substance abuse treatment · 2022Trial
- Improving the Delivery of Chronic Opioid Therapy Among People Living With Human Immunodeficiency Virus: A Cluster Randomized Clinical Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Trial
- Video directly observed therapy for patients receiving office-based buprenorphine - A pilot randomized controlled trial.Drug and alcohol dependence · 2021Trial
- A pilot study of mindful body awareness training as an adjunct to office-based medication treatment of opioid use disorder.Journal of substance abuse treatment · 2020Trial
- A randomized controlled trial of motivational interviewing tailored for heavy drinking latinxs.Journal of consulting and clinical psychology · 2019Trial
- Randomized pilot trial of Web-based cognitive-behavioral therapy adapted for use in office-based buprenorphine maintenance.Substance abuse · 2019Trial
- MySafeRx: a mobile technology platform integrating motivational coaching, adherence monitoring, and electronic pill dispensing for enhancing buprenorphine/naloxone adherence during opioid use disorder treatment: a pilot study.Addiction science & clinical practice · 2018Trial
- Treatment outcomes among a cohort of African American buprenorphine patients: Follow-up at 12 months.The American journal of drug and alcohol abuse · 2018Trial
- Hospitalized opioid-dependent patients: Exploring predictors of buprenorphine treatment entry and retention after discharge.The American journal on addictions · 2017Trial
- Improving Adherence to Long-term Opioid Therapy Guidelines to Reduce Opioid Misuse in Primary Care: A Cluster-Randomized Clinical Trial.JAMA internal medicine · 2017Trial
- Emergency Department-Initiated Buprenorphine for Opioid Dependence with Continuation in Primary Care: Outcomes During and After Intervention.Journal of general internal medicine · 2017Trial
- Buprenorphine Initiation and Linkage to Outpatient Buprenorphine do not Reduce Frequency of Injection Opiate Use Following Hospitalization.Journal of substance abuse treatment · 2016Trial
109 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundOpioid addiction is a chronic disease treatable in primary care settings with buprenorphine hydrochloride, but this treatment remains underused. We describe a collaborative care model for managing opioid addiction with buprenorphine hydrochloride-naloxone hydrochloride dihydrate sublingual tablets.
methodsOurs is a cohort study of patients treated for opioid addiction using collaborative care between nurse care managers and generalist physicians in an urban academic primary care practice during a 5-year period. We examine patient characteristics, 12-month treatment success (ie, retention or taper after 6 months), and predictors of successful outcomes.
resultsFrom September 1, 2003, through September 30, 2008, 408 patients with opioid addiction were treated with buprenorphine. Twenty-six patients were excluded from analysis because they left treatment owing to preexisting legal or medical conditions or a need to transfer to another buprenorphine program. At 1 year, 196 of 382 patients (51.3%) underwent successful treatment. Of patients remaining in treatment at 12 months, 154 of 169 (91.1%) were no longer using illicit opioids or cocaine based on urine drug test results. On admission, patients who were older, were employed, and used illicit buprenorphine had significantly higher odds of treatment success; those of African American or Hispanic/Latino race had significantly lower odds of treatment success. These outcomes were achieved with a model that facilitated physician involvement.
conclusionCollaborative care with nurse care managers in an urban primary care practice is an alternative and successful treatment method for most patients with opioid addiction that makes effective use of time for physicians who prescribe buprenorphine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.