ArticlePlant physiology2011
Wheat grain development is characterized by remarkable trehalose 6-phosphate accumulation pregrain filling: tissue distribution and relationship to SNF1-related protein kinase1 activity.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.
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Who cites it
91 citing papers in PubMed, 210 citations in OpenAlex.
- Salinity signaling networks in wheat: crosstalk among CaPlant signaling & behavior · 2026Review
- The old nourishes the new: 100 years of leaf senescence studies in Plant Physiology.Plant physiology · 2026Review
- HvPHO1 Controls a Glucose 1-Phosphate-SnRK1 Signalling Module That Coordinates Starch Accumulation in Barley Endosperm.Plant biotechnology journal · 2026Article
- Integrative multi-omics analysis uncovers the regulatory network of wheat grain development during grain filling.BMC plant biology · 2026Article
- Trehalose 6-phosphate - a central regulator at the crossroads of sugar signalling, metabolism, and development.The New phytologist · 2025Review
- Grain under pressure: Harnessing biochemical pathways to beat drought and heat in wheat.The Plant journal : for cell and molecular biology · 2025Review
- TaWUS-like-5D affects grain weight and filling by inhibiting the expression of sucrose and trehalose metabolism-related genes in wheat grain endosperm.Plant biotechnology journal · 2025Article
- Article
- Sucrose synthase dynamics and its potential role in heat stress tolerance in cereals.Frontiers in plant science · 2025Review
- Direct and indirect responses of the Arabidopsis transcriptome to an induced increase in trehalose 6-phosphate.Plant physiology · 2024Article
- Comparative Proteomic Analysis Provides New Insights into Improved Grain-filling in Ratoon Season Rice.Rice (New York, N.Y.) · 2024Article
- Sugar sensing in C4 source leaves: a gap that needs to be filled.Journal of experimental botany · 2024Review
- Tissue- and time-dependent metabolite profiles during early grain development under normal and high night-time temperature conditions.BMC plant biology · 2024Article
- Endogenous Hormone Levels and Transcriptomic Analysis Reveal the Mechanisms of Bulbil Initiation inInternational journal of molecular sciences · 2024Article
- Molecular mechanism of trehalose 6-phosphate inhibition of the plant metabolic sensor kinase SnRK1.Science advances · 2024Article
- Auxin and carbohydrate control flower bud development in Anthurium andraeanum during early stage of sexual reproduction.BMC plant biology · 2024Article
- DOMAIN OF UNKNOWN FUNCTION581-9 negatively regulates SnRK1 kinase activity.Plant physiology · 2024Article
- Spatial expression patterns of genes encoding sugar sensors in leaves of C4 and C3 grasses.Annals of botany · 2023Article
- TaTPP-7A positively feedback regulates grain filling and wheat grain yield through T6P-SnRK1 signalling pathway and sugar-ABA interaction.Plant biotechnology journal · 2023Article
- In vivo protein kinase activity of SnRK1 fluctuates in Arabidopsis rosettes during light-dark cycles.Plant physiology · 2023Article
31 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
Abstract
Trehalose 6-phosphate (T6P) is a sugar signal that regulates metabolism, growth, and development and inhibits the central regulatory SNF1-related protein kinase1 (SnRK1; AKIN10/AKIN11). To better understand the mechanism in wheat (Triticum aestivum) grain, we analyze T6P content and SnRK1 activities. T6P levels changed 178-fold 1 to 45 d after anthesis (DAA), correlating with sucrose content. T6P ranged from 78 nmol g(-1) fresh weight (FW) pregrain filling, around 100-fold higher than previously reported in plants, to 0.4 nmol g(-1) FW during the desiccation stage. In contrast, maximum SnRK1 activity changed only 3-fold but was inhibited strongly by T6P in vitro. To assess SnRK1 activity in vivo, homologs of SnRK1 marker genes in the wheat transcriptome were identified using Wheat Estimated Transcript Server. SnRK1-induced and -repressed marker genes were expressed differently pregrain filling compared to grain filling consistent with changes in T6P. To investigate this further maternal and filial tissues were compared pre- (7 DAA) and during grain filling (17 DAA). Strikingly, in vitro SnRK1 activity was similar in all tissues in contrast to large changes in tissue distribution of T6P. At 7 DAA T6P was 49 to 119 nmol g(-1) FW in filial and maternal tissues sufficient to inhibit SnRK1; at 17 DAA T6P accumulation was almost exclusively endospermal (43 nmol g(-1) FW) with 0.6 to 0.8 nmol T6P g(-1) FW in embryo and pericarp. The data show a correlation between T6P and sucrose overall that belies a marked effect of tissue type and developmental stage on T6P content, consistent with tissue-specific regulation of SnRK1 by T6P in wheat grain.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.