ReviewClinical orthopaedics and related research2011
Sex and gender considerations in male patients with osteoporosis.
Review in Clinical orthopaedics and related research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Metasynthesis of Patient Attitudes Toward Bone Densitometry.Journal of general internal medicine · 2018Pooled it
- Fecal and urinary incontinence in older men with hip fracture: a geriatric syndrome with prognostic significance.European geriatric medicine · 2026Article
- Gender disparities in the treatment and outcome of osteoporotic thoracolumbar vertebral fractures - results from the prospective EOFTT multicenter study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Pathophysiology and Molecular Signalling in Osteoporosis: Linking Risk Factors to Bone Loss.Journal of cellular and molecular medicine · 2026Review
- Development of a gender score and its association with treatment outcomes in fragility fracture patients screened through Ontario's Fracture Screening and Prevention Program.Archives of osteoporosis · 2026Article
- Frailty and osteosarcopenia in older men: a hidden vulnerability.BMC geriatrics · 2026Article
- How can we promote gender and sex equality in orthopaedics and traumatology surgery? Research avenues perspectives.Journal of orthopaedic surgery and research · 2025Review
- Vitamin K intake levels are associated with bone health in people aged over 50 years: a NHANES-based survey.Frontiers in medicine · 2024Article
- Age-dependent gender differences in the diagnosis and treatment of osteoporosis during hospitalization in patients with fragility fractures.BMC geriatrics · 2023Article
- Is the Postoperative Outcome after Intraarticular Distal Radius Fracture Influenced by Age and Gender? A PROM Study.Journal of clinical medicine · 2023Article
- Article
- Increased Risk of Temporomandibular Joint Disorder in Osteoporosis Patients: A Longitudinal Study.Frontiers in endocrinology · 2022Article
- Associations of Obesity Indices with Bone Mineral Densities and Risk of Osteoporosis Stratified Across Diabetic Vascular Disease in T2DM Patients.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Gender Differences in Osteoporosis: A Single-Center Observational Study.The world journal of men's health · 2021Article
- Attitudes toward bone health among rural-dwelling veterans identified as at risk of fracture: a qualitative analysis.JBMR plus · 2021Article
- Duration of Bisphosphonate Drug Holidays in Osteoporosis Patients: A Narrative Review of the Evidence and Considerations for Decision-Making.Journal of clinical medicine · 2021Review
- Osteoporosis in Men: A Review of an Underestimated Bone Condition.International journal of molecular sciences · 2021Review
- Changes in bone mineral density over 10 years in patients with early rheumatoid arthritis.RMD open · 2020Observational
- Prevalence of osteoporosis and osteopenia in an apparently healthy Indian population - a cross-sectional retrospective study.Osteoporosis and sarcopenia · 2018Article
- Equal treatment: no evidence of gender inequity in osteoporosis management in a coordinator-based fragility fracture screening program.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteoporosis remains underrecognized and undertreated in both men and women, but men who sustain fragility fractures experience greater morbidity and mortality. While men exhibit advanced comorbidity at the time of hip fracture presentation, there are distinct sex- and gender-specific factors related to the pathophysiology and treatment of osteoporosis that further influence morbidity and mortality. QUESTIONS/PURPOSES: With a selective review of the literature, we evaluated sex- and gender-based differences contributing to increased morbidity and mortality in men with osteoporosis. WHERE ARE WE NOW?: Sex-specific differences in bone biology and morphology may affect the pathophysiology of osteoporosis, choice of pharmacotherapy, and surgical implant selection. Additionally, estrogen metabolism may play a key role in both fracture prevention and healing. Gender-based differences in recommendations for screening and prevention between men and women may influence the severity at which osteoporosis is recognized. Primary, secondary, and tertiary prevention efforts in men lag behind those of women. This may be due to a lack of consensus regarding screening guidelines for osteoporosis in men but may be attributed to lack of awareness in the physician and patient about osteoporosis and its potentially debilitating consequences. WHERE DO WE NEED TO GO?: These disparities are a call to action for healthcare providers to raise awareness for early prevention and treatment of this potentially debilitating disease, particularly in men. HOW DO WE GET THERE?: Continued prospective research on the differences between men and women diagnosed with osteoporosis is needed, as well as sex-specific stratification of data in all studies on osteoporosis.
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