ArticleDevelopment genes and evolution2011
Decapentaplegic (dpp) regulates the growth of a morphological novelty, beetle horns.
Article in Development genes and evolution, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- The cellular substrate of evolutionary novelty.Current biology : CB · 2025Review
- Co-option of stress mechanisms in the origin of evolutionary novelties.Evolution; international journal of organic evolution · 2022Article
- Notch signaling patterns head horn shape in the bull-headed dung beetle Onthophagus taurus.Development genes and evolution · 2020Article
- Article
- On the specificity of gene regulatory networks: How does network co-option affect subsequent evolution?Current topics in developmental biology · 2020Review
- Species diversity vs. morphological disparity in the light of evolutionary developmental biology.Annals of botany · 2016Review
- Hox proteins coordinate peripodial decapentaplegic expression to direct adult head morphogenesis in Drosophila.Developmental biology · 2012Article
- Pangolin expression influences the development of a morphological novelty: beetle horns.Genesis (New York, N.Y. : 2000) · 2012Article
- Epigenetic mechanisms underlying developmental plasticity in horned beetles.Genetics research international · 2012Article
- Article
- Shape--but not size--codivergence between male and female copulatory structures in Onthophagus beetles.PloS one · 2011Article
- Beetle horns and horned beetles: emerging models in developmental evolution and ecology.Wiley interdisciplinary reviews. Developmental biologyReview
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2 authors at 1 institution in 1 country.
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Abstract
Studies focusing on the development of morphological novelties suggest that patterning genes underlying traditional appendage development (i.e. mouthparts, legs, and wings) also play important roles in patterning novel morphological structures. In this study, we examine whether the expression and function of a member of the TGF-β signaling pathway, decapentaplegic (dpp), promotes development of a morphologically novel structure: beetle horns. Beetle horns are complex secondary sexual structures that develop in the head and/or prothorax, lack obvious homology to other insect outgrowths, and vary remarkably between species and sexes. We studied dpp expression through in situ hybridization, performed functional analyses with RNA interference, and gathered allometric measurements to determine the role of dpp during both pronotal and head horn development in both sexes of two morphologically dissimilar species in the Onthophagus genus, Onthophagus binodis and Onthophagus sagittarius. Our findings show that in addition to affecting growth and patterning of traditional appendages, dpp regulates beetle horn growth and remodeling.
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