Evidence map›Paper›PMID 21399478›Full record

ArticleAIDS (London, England)2011

Psychiatric correlates of HAART utilization and viral load among HIV-positive impoverished persons.

Adam W Carrico, David R Bangsberg, Sheri D Weiser, Maggie Chartier, Samantha E Dilworth, Elise D Riley

Open access · greenAbstract readValidation Study
In one paragraph

Article in AIDS (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 5 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 5 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Adam W CarricoUniversity of California, San Francisco Center for AIDS Prevention Studies, California, USA. adam.carrico@ucsf.edu
David R Bangsberg
Sheri D Weiser
Maggie Chartier
Samantha E Dilworth
Elise D Riley
University of California, San Francisco · USMassachusetts General Hospital · USSan Francisco General Hospital · USSan Francisco VA Medical Center · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
TB PREVENTION AND HIV IN THE HOMELESS--AN INTERVENTIONR01MH054907 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BANGSBERG, DAVID ROY · 1995 to 2014
$20.7M
Effects of housing and HIV on risk behavior and victimization of indigent womenR01DA015605 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RILEY, ELISE D. · 2003 to 2011
$3.9M
NCRR NIH HHS UL1 RR024131NIDA NIH HHS R01 DA015605NIDA NIH HHS R01-DA15605NIMH NIH HHS R01 MH054907NIMH NIH HHS R01-MH54907
6 · The paper itself

Abstract

objectiveResearch on the role psychiatric factors in HIV disease management has yielded discrepant findings, possibly because prior studies did not include comprehensive psychiatric screeners. This study administered a validated screener to examine psychiatric correlates of highly active antiretroviral therapy (HAART) utilization and viral load.

designCommunity-recruited, HIV-positive impoverished persons provided sociodemographic information, completed a Diagnostic Interview Schedule that screened for psychiatric disorders, and provided a blood sample to measure HIV disease markers.

methodsIn this cross-sectional investigation with 227 participants, a multiple logistic regression model examined correlates of HAART utilization compared to a reference group that was eligible for (i.e. CD4(+) cell count <350 cells/μl) but not taking HAART. A multiple linear regression model examined correlates of HIV viral load among 147 participants on HAART.

resultsSleeping on the street [adjusted OR (AOR) = 0.06; 95% confidence interval (CI) = 0.01–0.26] and screening positive for a stimulant use disorder (AOR = 0.29; 95% CI = 0.13–0.65) were independently associated with lower odds of HAART utilization. Conversely, enrollment in the AIDS Drug Assistance Program (AOR = 3.94; 95% CI = 1.45–10.73) and receipt of mental health treatment (AOR = 4.78; 95% CI = 1.77–12.87) were independently associated with increased odds of HAART utilization. Among those on HAART, screening positive for a severe mental illness was independently associated with a six-fold higher viral load.

conclusionProviding psychiatric treatment could optimize health outcomes among HIV-positive impoverished persons and boost the effectiveness of 'test and treat' approaches to HIV prevention.

Indexed as

PovertyAdultAgedAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountCross-Sectional StudiesFemaleHIV InfectionsHumansMaleMiddle AgedSan FranciscoViral Load

Identifiers

PMID21399478
PMCPMC3601574
OpenAlexW2037263552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.