Evidence map›Paper›PMID 21399234›Full record

ReviewOncotarget2011

Recent advances in anti-angiogenic therapy of cancer.

Rajeev S Samant, Lalita A Shevde

Abstract readReview
In one paragraph

Review in Oncotarget, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  17. Monitoring antiangiogenesis of bevacizumab in zebrafish.Drug design, development and therapy · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rajeev S SamantMitchell Cancer Institute, University of South Alabama, Mobile, AL, USA. rsamant@usouthal.edu
Lalita A Shevde

Funding

Role of Nmi in retarding breast tumor growth.R01CA140472 · NCI · UNIVERSITY OF SOUTH ALABAMA · PI SAMANT, RAJEEV S · 2010 to 2014
$1.3M
NCI NIH HHS 1R01CA140472-01A1NCI NIH HHS R01 CA140472
6 · The paper itself

Abstract

Since angiogenesis is critical for tumor growth and metastasis, anti-angiogenic treatment is a highly promising therapeutic approach. Thus, for over last couple of decades, there has been a robust activity aimed towards the discovery of angiogenesis inhibitors. More than forty anti-angiogenic drugs are being tested in clinical trials all over the world. This review discusses agents that have approved by the FDA and are currently in use for treating patients either as single-agents or in combination with other chemotherapeutic agents.

Indexed as

Angiogenesis InhibitorsAnimalsAntibodies, MonoclonalHumansNeoplasmsNeovascularization, PathologicAngiogenesis InhibitorsAntibodies, Monoclonal

Identifiers

PMID21399234
PMCPMC3260813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.