Evidence map›Paper›PMID 21398223›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2011

The association between a journal's source of revenue and the drug recommendations made in the articles it publishes.

Annette Becker, Fatma Dörter, Kirsten Eckhardt, Annika Viniol, Erika Baum, Michael M Kochen, Joel Lexchin, Karl Wegscheider, Norbert Donner-Banzhoff

Abstract readComparative Study
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Covert pharmaceutical promotion in free medical journals.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2011
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Annette BeckerDepartment of General Practice, Preventive and Rehabilitative Medicine, University of Marburg, Marburg, Germany. annette.becker@staff.uni-marburg.de
Fatma Dörter
Kirsten Eckhardt
Annika Viniol
Erika Baum
Michael M Kochen
Joel Lexchin
Karl Wegscheider
Norbert Donner-Banzhoff

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is evidence to suggest that pharmaceutical companies influence the publication and content of research papers. Most German physicians rely on journals for their continuing medical education. We studied the influence of pharmaceutical advertising on the drug recommendations made in articles published in 11 German journals that focus on continuing medical education.

methodsWe conducted a cross-sectional study of all of the issues of 11 journals published in 2007. Only journals frequently read by general practitioners were chosen. Issues were screened for pharmaceutical advertisements and recommendations made in the editorial content for a specified selection of drugs. Each journal was rated on a five-point scale according to the strength with which it either recommended or discouraged the use of these drugs. We looked for differences in these ratings between free journals (i.e., those financed entirely by pharmaceutical advertising), journals with mixed sources of revenue and journals financed solely by subscription fees. The journals were also screened for the simultaneous appearance of advertisements and recommendations for the same drug within a certain period, which was adjusted for both journal and class of drug.

resultsWe identified 313 issues containing at least one advertisement for the selected drugs and 412 articles in which drug recommendations were made. Free journals were more likely to recommend the specified drugs than journals with sources of revenue that were mixed or based solely on subscriptions. The simultaneous appearance of advertisements and recommendations for the same drug in the same issue of a journal showed an inconsistent association.

interpretationFree journals almost exclusively recommended the use of the specified drugs, whereas journals financed entirely with subscription fees tended to recommend against the use of the same drugs. Doctors should be aware of this bias in their use of material published in medical journals that focus on continuing medical education.

Indexed as

AdvertisingCross-Sectional StudiesDrug IndustryGeneral PracticeGermanyHumansLogistic ModelsPeriodicals as TopicPractice Patterns, Physicians'Quality Control

Identifiers

PMID21398223
PMCPMC3060182

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.