Evidence map›Paper›PMID 21398201›Full record

ArticleEnvironmental health perspectives2011

Acute effects of fine particulate air pollution on cardiac arrhythmia: the APACR study.

Fan He, Michele L Shaffer, Sol Rodriguez-Colon, Jeff D Yanosky, Edward Bixler, Wayne E Cascio, Duanping Liao

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 70 citations in OpenAlex.

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  9. Diurnal variability of fine-particulate pollution concentrations: data from 14 low- and middle-income countries.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2021
    Article
  10. Article
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  12. Air Pollution-Induced Autonomic Modulation.Physiology (Bethesda, Md.) · 2020
    Review
  13. Associations between air pollution and outpatient visits for allergic rhinitis in Xinxiang, China.Environmental science and pollution research international · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fan HeDepartment of Public Health Sciences, the Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA.
Michele L Shaffer
Sol Rodriguez-Colon
Jeff D Yanosky
Edward Bixler
Wayne E Cascio
Duanping Liao
Pennsylvania State University · USEast Carolina University · US

Funding

Air Pollution and Cardiac Risk: Mechanisms & Time-courseR01ES014010 · NIEHS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LIAO, DUANPING · 2007 to 2010
$1.1M
NIEHS NIH HHS 1 R01 ES014010NIEHS NIH HHS R01 ES014010
6 · The paper itself

Abstract

backgroundThe mechanisms underlying the relationship between particulate matter (PM) air pollution and cardiac disease are not fully understood.

objectivesWe examined the effects and time course of exposure to fine PM [aerodynamic diameter ≤ 2.5 μm (PM(2.5))] on cardiac arrhythmia in 105 middle-age community-dwelling healthy nonsmokers in central Pennsylvania.

methodsThe 24-hr beat-to-beat electrocardiography data were obtained using a high-resolution Holter system. After visually identifying and removing artifacts, we summarized the total number of premature ventricular contractions (PVCs) and premature atrial contractions (PACs) for each 30-min segment. A personal PM(2.5) nephelometer was used to measure individual-level real-time PM(2.5) exposures for 24 hr. We averaged these data to obtain 30-min average time-specific PM(2.5) exposures. Distributed lag models under the framework of negative binomial regression and generalized estimating equations were used to estimate the rate ratio between 10-μg/m³ increases in average PM(2.5) over 30-min intervals and ectopy counts.

resultsThe mean ± SD age of participants was 56 ± 8 years, with 40% male and 73% non-Hispanic white. The 30-min mean ± SD for PM(2.5) exposure was 13 ± 22 μg/m³, and PAC and PVC counts were 0.92 ± 4.94 and 1.22 ± 7.18. Increases of 10 μg/m³ in average PM(2.5) concentrations during the same 30 min or the previous 30 min were associated with 8% and 3% increases in average PVC counts, respectively. PM(2.5) was not significantly associated with PAC count.

conclusionPM(2.5) exposure within approximately 60 min was associated with increased PVC counts in healthy individuals.

Indexed as

Air PollutantsAir PollutionElectrocardiographyFemaleHumansInhalation ExposureMaleMiddle AgedParticulate MatterPennsylvaniaTime FactorsVentricular Premature ComplexesAir PollutantsParticulate Matter

Identifiers

PMID21398201
PMCPMC3222979
OpenAlexW1966029354

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.