Evidence map›Paper›PMID 21397103›Full record

ArticlePsychosomatics

The association of comorbid depression with intensive care unit admission in patients with diabetes: a prospective cohort study.

Dimitry S Davydow, Joan E Russo, Evette Ludman, Paul Ciechanowski, Elizabeth H B Lin, Michael Von Korff, Malia Oliver, Wayne J Katon

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Psychosomatics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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  14. Symptoms of depression in survivors of severe sepsis: a prospective cohort study of older Americans.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dimitry S DavydowDept. of Psychiatry and Behavioral Sciences, University of Washington, School of Medicine, Seattle, WA 98195, USA. ddavydo1@u.washington.edu
Joan E Russo
Evette Ludman
Paul Ciechanowski
Elizabeth H B Lin
Michael Von Korff
Malia Oliver
Wayne J Katon
Kaiser Permanente Washington Health Research Institute · USUniversity of Washington · US

Funding

INSTITUTE FOR TRANSLATIONAL HEALTH SCIENCE (UL1): BPCAUL1RR025014 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$51.5M
Psychiatry Primary Care NRSA T-32 AwardT32MH020021 · NIMH · UNIVERSITY OF WASHINGTON · PI JOHN C. FORTNEY, JURGEN UNUTZER · 1998 to 2026
$5.6M
Depression-Diabetes Care Disparities, Adverse OutcomesR01MH073686 · NIMH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2005 to 2008
$1.8M
Population-Based Psychiatric Intervention--Primary CareK24MH069471 · NIMH · UNIVERSITY OF WASHINGTON · PI KATON, WAYNE J · 2004 to 2011
$1.0M
Quality Improvement of School Mental Health ServicesK08MH069741 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KATAOKA, SHERYL H · 2004 to 2008
$769k
NCRR NIH HHS UL1 RR025014NIMH NIH HHS K08 MH069741NIMH NIH HHS K24 MH069471NIMH NIH HHS K24MH069741-07NIMH NIH HHS R01 MH073686NIMH NIH HHS R01MH073686-04NIMH NIH HHS T32 MH020021NIMH NIH HHS T32/MH20021-12
6 · The paper itself

Abstract

backgroundIt is unknown if comorbid depression in patients with diabetes mellitus increases the risk of intensive care unit (ICU) admission.

objectiveThis study examined whether comorbid depression in patients with diabetes increased risk of ICU admission, coronary care unit (CCU) admission, and general medical-surgical unit hospitalization, as well as total days hospitalized, after controlling for demographics, clinical characteristics, and health risk behaviors.

methodThis prospective cohort study included 3,596 patients with diabetes enrolled in the Pathways Epidemiologic Follow-Up Study. We assessed baseline depression with the Patient Health Questionnaire-9. We controlled for baseline demographics, smoking, BMI, exercise, hemoglobin A(1c), medical comorbidities, diabetes complications, type 1 diabetes, diabetes duration, and insulin treatment. We assessed time to any ICU, CCU, and/or general medical-surgical unit admission using Cox proportional-hazards regression. We used Poisson regression with robust standard errors to examine associations between depression and total days hospitalized.

resultsUnadjusted analyses revealed that baseline probable major depression was associated with increased risk of ICU admission [hazard ratio (HR) 1.94, 95% confidence interval (95% CI)(1.34-2.81)], but was not associated with CCU or general medical-surgical unit admission. Fully adjusted analyses revealed probable major depression remained associated with increased risk of ICU admission [HR 2.23, 95% CI(1.45-3.45)]. Probable major depression was also associated with more total days hospitalized (Incremental Relative Risk 1.64, 95%CI(1.26-2.12)).

conclusionsPatients with diabetes and comorbid depression have a greater risk of ICU admission. Improving depression treatment in patients with diabetes could potentially prevent hospitalizations for critical illnesses and lower healthcare costs.

Indexed as

Intensive Care UnitsAnalysis of VarianceChi-Square DistributionComorbidityConfounding Factors, EpidemiologicDiabetes MellitusFemaleHumansMajor Depressive DisorderMaleMiddle AgedPatient AdmissionPoisson DistributionProportional Hazards ModelsProspective StudiesRisk Factors

Identifiers

PMID21397103
PMCPMC3073638
OpenAlexW2079508984

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.