Evidence map›Paper›PMID 21396945›Full record

ReviewNeuropharmacology2012

Treating nightmares and insomnia in posttraumatic stress disorder: a review of current evidence.

Carla M Nappi, Sean P A Drummond, Joshua M H Hall

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Neuropharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
10.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04198142 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Treatment of Nightmares in Psychiatric Inpatients With Imagery Rehearsal Therapy: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of ZurichRan2019 to 2020Enrolled60ConditionsNightmare, Psychiatric DisorderArmsImagery Rehearsal Therapy, Treatment as Usual with dream diaries
NCT04201392 unknown statusnot on this mapstarted 2018, after this paper: background citation

Prevalence and Characteristics of Sleep Disturbances Among Psychiatric Inpatients

TypeobservationalSponsorUniversity of ZurichRan2018 to 2020Enrolled120ConditionsSleep Disturbance, Sleep Disorder, Insomnia, Hypersomnia
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 133 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Posttraumatic stress disorder (PTSD), sleep, and cardiovascular disease risk: A mechanism-focused narrative review.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022
    Review
  15. Article
  16. Review
  17. Postmigration stress and sleep disturbances mediate the relationship between trauma exposure and posttraumatic stress symptoms among Syrian and Iraqi refugees.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  18. Article
  19. Article
  20. Treatment of Sleep Comorbidities in Posttraumatic Stress Disorder.Current treatment options in psychiatry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Carla M NappiUniversity of California, San Diego and Veterans Affairs San Diego Healthcare System, 3350 La Jolla Village Drive, MC116B, San Diego, CA 92161, United States. cnappi@ucsd.edu
Sean P A Drummond
Joshua M H Hall
University of California, San Diego · USVA San Diego Healthcare System · US

Funding

Treating Insomnia & Nightmares After Trauma: Impact on Symptoms & Quality of LifeRC1NR011728 · NINR · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI DRUMMOND, SEAN P.A. · 2009 to 2010
$962k
NINR NIH HHS RC1 NR011728
6 · The paper itself

Abstract

Emerging evidence supports the notion of disrupted sleep as a core component of Posttraumatic Stress Disorder (PTSD). Effective treatments for nighttime PTSD symptoms are critical because sleep disruption may be mechanistically linked to development and maintenance of PTSD and is associated with significant distress, functional impairment, and poor health. This review aimed to describe the state of science with respect to the impact of the latest behavioral and pharmacological interventions on posttraumatic nightmares and insomnia. Published studies that examined evidence for therapeutic effects upon sleep were included. Some behavioral and pharmacological interventions show promise, especially for nightmares, but there is a need for controlled trials that include valid sleep measures and are designed to identify treatment mechanisms. Our ability to treat PTSD-related sleep disturbances may be improved by moving away from considering sleep symptoms in isolation and instead conducting integrative studies that examine sequential or combined behavioral and/or pharmacological treatments targeting both the daytime and nighttime aspects of PTSD. This article is part of a Special Issue entitled 'Post-Traumatic Stress Disorder'.

Indexed as

Antidepressive AgentsAntipsychotic AgentsBehavior TherapyDreamsHumansHypnotics and SedativesSleep Initiation and Maintenance DisordersStress Disorders, Post-TraumaticTreatment OutcomeAntidepressive AgentsAntipsychotic AgentsHypnotics and Sedatives

Identifiers

PMID21396945
PMCPMC5154613
OpenAlexW2043619743

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.