ReviewTrials2011
Using a business model approach and marketing techniques for recruitment to clinical trials.
Review in Trials, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 63 citations in OpenAlex.
- Trial
- Recruitment strategies in two reproductive medicine network infertility trials.Contemporary clinical trials · 2015Trial
- Participant recruitment into a randomised controlled trial of exercise therapy for people with multiple sclerosis.Trials · 2015Trial
- A study protocol for Truce: a pragmatic controlled trial of a seven-week acceptance and commitment therapy program for young people who have a parent with cancer.BMC psychology · 2015Trial
- Clinical trial management of participant recruitment, enrollment, engagement, and retention in the SMART study using a Marketing and Information Technology (MARKIT) model.Contemporary clinical trials · 2015Trial
- Trial
- Challenges and success of recruiting and retention for a culturally tailored diabetes prevention program for adults of Mexican descent.The Diabetes educatorTrial
- "The more I know, the more you know" Using culturally responsive marketing strategies to develop tools that increase awareness about clinical trials among Black communities.BMC public health · 2025Article
- Usage and perceived effectiveness of recruitment techniques among clinical trials recruiters.Journal of clinical and translational science · 2025Article
- Leveraging Single-Case Experimental Designs to Promote Personalized Psychological Treatment: Step-by-Step Implementation Protocol with Stakeholder Involvement of an Outpatient Clinic for Personalized Psychotherapy.Administration and policy in mental health · 2024Article
- Randomised trials conducted using cohorts: a scoping review.BMJ open · 2024Article
- Principal Investigators' Perceptions on Factors Associated with Successful Recruitment in Clinical Trials.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2023Article
- Uncovering key clinical trial features influencing recruitment.Journal of clinical and translational science · 2023Article
- Value and engagement: what can clinical trials learn from techniques used in not-for-profit marketing?Trials · 2022Article
- Recruitment cost and outcomes for an arthritis work disability prevention randomized clinical trial: The Work It study.Contemporary clinical trials communications · 2021Article
- Recruitment in Health Services Research-A Study on Facilitators and Barriers for the Recruitment of Community-Based Healthcare Providers.International journal of environmental research and public health · 2021Article
- Placebo comparator group selection and use in surgical trials: the ASPIRE project including expert workshop.Health technology assessment (Winchester, England) · 2021Article
- Age specific recruitment and retention to a large multicentre observational breast cancer trial in older women: The Age Gap Trial.Journal of geriatric oncology · 2021Article
- Key components and IT assistance of participant management in clinical research: a scoping review.JAMIA open · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Randomised controlled trials (RCTs) are generally regarded as the gold standard for evaluating health care interventions. The level of uncertainty around a trial's estimate of effect is, however, frequently linked to how successful the trial has been in recruiting and retaining participants. As recruitment is often slower or more difficult than expected, with many trials failing to reach their target sample size within the timescale and funding originally envisaged, the results are often less reliable than they could have been. The high number of trials that require an extension to the recruitment period in order to reach the required sample size potentially delays the introduction of more effective therapies into routine clinical practice. Moreover, it may result in less research being undertaken as resources are redirected to extending existing trials rather than funding additional studies.Poor recruitment to publicly-funded RCTs has been much debated but there remains remarkably little clear evidence as to why many trials fail to recruit well, which recruitment methods work, in which populations and settings and for what type of intervention. One proposed solution to improving recruitment and retention is to adopt methodology from the business world to inform and structure trial management techniques.We review what is known about interventions to improve recruitment to trials. We describe a proposed business approach to trials and discuss the implementation of using a business model, using insights gained from three case studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.