Integrin antagonists for transplant immunosuppression: panacea or peril?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. Activation and regulation of alloreactive T cell immunity in solid organ transplantation.Nature reviews. Nephrology · 2022
   Review
2. Memory T Cells in Transplantation: Old Challenges Define New Directions.Transplantation · 2020
   Review
3. Selective CD28 blockade attenuates CTLA-4-dependent CD8+ memory T cell effector function and prolongs graft survival.JCI insight · 2018
   Article
4. Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy.Immunological reviews · 2017
   Review
5. Role of Memory T Cells in Allograft Rejection and Tolerance.Frontiers in immunology · 2017
   Review
6. Costimulation blockade: current perspectives and implications for therapy.Transplantation · 2013
   Review
7. Transient combination therapy targeting the immune synapse abrogates T cell responses and prolongs allograft survival in mice.PloS one · 2013
   Article
8. Combined costimulatory and leukocyte functional antigen-1 blockade prevents transplant rejection mediated by heterologous immune memory alloresponses.Transplantation · 2012
   Article
9. The impact of infection and tissue damage in solid-organ transplantation.Nature reviews. Immunology · 2012
   Review
10. Heterogeneity within T Cell Memory: Implications for Transplant Tolerance.Frontiers in immunology · 2012
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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