Evidence map›Paper›PMID 21395205›Full record

ArticleParasite (Paris, France)2011

Histamine and TNF-alpha release by rat peritoneal mast cells stimulated with Trichomonas vaginalis.

S J Im, M H Ahn, I H Han, H O Song, Y S Kim, H M Kim, J S Ryu

Open access · hybridAbstract read
In one paragraph

Article in Parasite (Paris, France), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Anti-Inflammatory Effects of aMolecules (Basel, Switzerland) · 2020
    Article
  5. Article
  6. Frontiers in microbiology · 2018
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

S J ImDepartment of Environmental Biology and Medical Parasitology, Hanyang University College of Medicine, #17 Haengdang-dong, Sungdong-gu, Seoul 133-791, Korea.
M H Ahn
I H Han
H O Song
Y S Kim
H M Kim
J S Ryu
Hanyang University · KRCatholic University of Daegu · KRKyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mast cells have been reported to be predominant in the vaginal smears of patients infected with T. vaginalis. In this study, we investigated whether T. vaginalis could induce mast cells to migrate and to produce TNF-alpha and histamine. Rat peritoneal mast cells (RPMC), a primary mast cell, were used for the study. T. vaginalis induced an increase in chemotactic migration of the mast cells toward excretory and secretory product (ESP) of T. vaginalis, and the mast cells activated with T. vaginalis showed an increased release of histamine and TNF-alpha. Therefore, mast cells may be involved in the inflammatory response caused by T. vaginalis.

Indexed as

AnimalsChemotaxisCytoplasmic GranulesExocytosisHistamineHistamine ReleaseMast CellsMicroscopy, Electron, TransmissionPeritoneal CavityRatsRats, WistarTrichomonas vaginalisTumor Necrosis Factor-alphaHistamineTumor Necrosis Factor-alpha

Identifiers

PMID21395205
PMCPMC3671398
OpenAlexW1972518218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.