Trial reportEuropean journal of applied physiology2011
Effect of fitness and physical activity on bone mass in adolescents: the HELENA Study.
Trial report in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Association Between Muscular Strength and Bone Health from Children to Young Adults: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- NEUROMUSCULAR FITNESS IN EARLY LIFE AND ITS IMPACT ON BONE HEALTH IN ADULTHOOD: A SYSTEMATIC REVIEW.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2020Pooled it
- The health benefits of muscular fitness for children and adolescents: a systematic review and meta-analysis.Sports medicine (Auckland, N.Z.) · 2014Pooled it
- Lower body muscular strength as a predictor of health indicators in youth population: A systematic review and meta-analysis.Sports medicine and health science · 2026Review
- The associations between speed performance and health outcomes in children and adolescents: A systematic review and meta-analysis.Journal of exercise science and fitness · 2026Review
- Physical fitness changes among school-aged children during the COVID-19 lockdown evaluated within the Hungarian National Student Fitness Test cohort.Scientific reports · 2026Article
- Outline: The Long-Term Impact of Exercise on Adolescent Growth and Development.Advances in experimental medicine and biology · 2026Review
- The effects of combined endurance training of different intensities and resistance training on bone mineral density, microstructure and mechanical properties of rats.Frontiers in endocrinology · 2026Article
- The Role of Muscular Fitness on Bone Mineral Content and Areal Bone Mineral Density in Youth With Type 1 Diabetes.The Journal of clinical endocrinology and metabolism · 2025Article
- The Impact of Physical Education Attendance and Diet on Bone Mineralization in Adolescents.Nutrients · 2025Article
- Physical fitness is associated with fat mass and muscle mass in Chinese preschoolers.BMC public health · 2025Article
- Impact of outer width of the metacarpal diaphysis on the identification of low bone mass in children.PloS one · 2025Article
- Muscle strength deficits are associated with low bone mineral density in young pediatric cancer survivors: The iBoneFIT project.Journal of sport and health science · 2024Article
- Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood.BMC public health · 2023Article
- Speed, agility, and musculoskeletal fitness are independently associated with areal bone mineral density in children.Frontiers in physiology · 2023Article
- Testing the Functional Model of Bone Development: Direct and Mediating Role of Muscle Strength on Bone Properties in Growing Youth.International journal of environmental research and public health · 2021Article
- Article
- Precision exercise medicine: predicting unfavourable status and development in the 20-m shuttle run test performance in adolescence with machine learning.BMJ open sport & exercise medicine · 2021Article
- The effect of an online exercise programme on bone health in paediatric cancer survivors (iBoneFIT): study protocol of a multi-centre randomized controlled trial.BMC public health · 2020Article
- Differences in areal bone mineral density between metabolically healthy and unhealthy overweight/obese children: the role of physical activity and cardiorespiratory fitness.Pediatric research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our aim is to analyse the effect on bone mass of: (1) physical fitness performance on a specific group of physical activity (PA) and, (2) PA on a specific physical fitness performance group. Bone mineral content (BMC) by dual energy X-ray absorptiometry (DXA) and PA by accelerometers was assessed in 373 Spanish adolescents (182 males). Adolescents were classified as: active and non-active (≥60 or <60 min day(-1) of moderate-vigorous PA). Fitness was assessed through speed/agility, strength and cardiorespiratory tests. Adolescents were classified by tertiles (T1, T2 and T3). ANCOVA was used for the analysis with sex, height, lean mass, calcium intake and pubertal status as covariates. Adolescents with lower strength, speed/agility and cardiorespiratory fitness (CRF) showed lower BMC in the whole body and extremities compared with adolescents with better results in these tests, mainly those non-active adolescents. Non-active adolescents with high fitness levels showed higher BMC (whole body and upper limbs) than active ones. The conclusions included: (1) within the non-active group, lower levels of fitness were associated with lower BMC; this might be through PA or trough an effect of PA on muscle mass. (2) Non-active adolescents with high level of fitness in most fitness tests showed higher BMC than their active peers, in spite of their lower PA levels. These unexpected results could be influenced by several factors such as genetics, nutrition, type of exercise or sport, hormones and skeletal age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.