Evidence map›Paper›PMID 21394615›Full record

ReviewThe international journal of cardiovascular imaging2011

Optical coherence tomography endpoints in stent clinical investigations: strut coverage.

Satoko Tahara, Daniel Chamié, Motaz Baibars, Chadi Alraies, Marco Costa

Open access · greenAbstract readReview
In one paragraph

Review in The international journal of cardiovascular imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Drug-eluting metallic stents in urology.Indian journal of urology : IJU : journal of the Urological Society of India · 2014
    Review
  11. Article
  12. Article
  13. Article
  14. Cardiovascular imaging 2011 in the International Journal of Cardiovascular Imaging.The international journal of cardiovascular imaging · 2012
    Review
  15. QCA, IVUS and OCT in interventional cardiology in 2011.Cardiovascular diagnosis and therapy · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Satoko TaharaCardiovascular Research Core Laboratory, University Hospitals Case Medical Center, Cleveland, OH 44106-5038, USA.
Daniel Chamié
Motaz Baibars
Chadi Alraies
Marco Costa
University Hospitals Case Medical Center · US

Funding

In vivo Characterization of Stents using Intravascular OCT ImagingR01HL114406 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI BEZERRA, HIRAM, ROLLINS, ANDREW MARTIN · 2013 to 2016
$1.7M
Coronary Plaque Characterization with Vascular OCT ImagingR21HL108263 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI COSTA, MARCO A, WILSON, DAVID LYNN · 2011 to 2012
$423k
NHLBI NIH HHS R01 HL114406NHLBI NIH HHS R21 HL108263
6 · The paper itself

Abstract

Late stent thrombosis (LST) and very LST (VLST) are infrequent complications after drug-eluting stent (DES) implantation, but they carry a significant risk for patients. Delayed healing, which may be represented by incomplete stent coverage, has been observed in necropsy vessel specimens treated with DES. As a result, in vivo assessment of stent coverage, as well as stent apposition using optical coherence tomography (OCT), have been recently used as surrogate safety endpoints in clinical trials testing DES platforms. By adopting strut coverage assessed by OCT, one can assess the safety profile of the new generation of DES in preregistration studies. This article focuses on stent strut coverage as a central predictor of late DES thrombosis from the histopathological point of view, discusses the limitations of the current imaging modalities and presents the technical characteristics of OCT for the detection of neointimal coverage after stent implantation. We also review the preclinical and clinical investigations using this novel imaging modality.

Indexed as

Drug-Eluting StentsTomography, Optical CoherenceAngioplasty, Balloon, CoronaryAnimalsCoronary Artery DiseaseHumansImage Interpretation, Computer-AssistedPredictive Value of TestsProsthesis DesignSeverity of Illness IndexThrombosisTime FactorsTreatment OutcomeWound Healing

Identifiers

PMID21394615
PMCPMC4459645
OpenAlexW1971101640

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.