Evidence map›Paper›PMID 21394502›Full record

ArticleEuropean biophysics journal : EBJ2011

Cancer physics: diagnostics based on damped cellular elastoelectrical vibrations in microtubules.

Jiří Pokorný, Clarbruno Vedruccio, Michal Cifra, Ondřej Kučera

Abstract read
PubMed Publisher
In one paragraph

Article in European biophysics journal : EBJ, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
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  6. Mitochondrial Dysfunction and Disturbed Coherence: Gate to Cancer.Pharmaceuticals (Basel, Switzerland) · 2015
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jiří PokornýInstitute of Photonics and Electronics, Academy of Sciences of the Czech Republic, Chaberská 57, 18251 Prague 8, Czech Republic. pokorny@ufe.cz
Clarbruno Vedruccio
Michal Cifra
Ondřej Kučera
Czech Academy of Sciences, Institute of Photonics and Electronics · CZCzech Technical University in Prague · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper describes a proposed biophysical mechanism of a novel diagnostic method for cancer detection developed recently by Vedruccio. The diagnostic method is based on frequency selective absorption of electromagnetic waves by malignant tumors. Cancer is connected with mitochondrial malfunction (the Warburg effect) suggesting disrupted physical mechanisms. In addition to decreased energy conversion and nonutilized energy efflux, mitochondrial malfunction is accompanied by other negative effects in the cell. Diminished proton space charge layer and the static electric field around the outer membrane result in a lowered ordering level of cellular water and increased damping of microtubule-based cellular elastoelectrical vibration states. These changes manifest themselves in a dip in the amplitude of the signal with the fundamental frequency of the nonlinear microwave oscillator-the core of the diagnostic device-when coupled to the investigated cancerous tissue via the near-field. The dip is not present in the case of healthy tissue.

Indexed as

Electromagnetic FieldsBiophysicsCase-Control StudiesElasticityElectricityHumansMicrotubulesMicrowavesNeoplasmsVibrationWaterWater

Identifiers

PMID21394502
OpenAlexW1999648073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.