ArticleJournal of perinatology : official journal of the California Perinatal Association2011
Diuretics for very low birth weight infants in the first 28 days: a survey of the U.S. neonatologists.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02469597 (Single Dose of Furosemide to Improve Respiratory Distress in Moderate to Severe Bronchiolitis), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Single Dose of Furosemide to Improve Respiratory Distress in Moderate to Severe Bronchiolitis
Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Advancements in research on fluid overload in preterm infants-a narrative review.Frontiers in pediatrics · 2025Review
- Diuretic drug utilization in neonates: a French prescription database analysis.Frontiers in pharmacology · 2024Article
- Use of diuretics in the neonatal period.Pediatric nephrology (Berlin, Germany) · 2021Review
- Risk factors for metabolic bone disease among preterm infants less than 32 weeks gestation with Bronchopulmonary dysplasia.BMC pediatrics · 2021Article
- Loop Diuretics in Severe Bronchopulmonary Dysplasia: Cumulative Use and Associations with Mortality and Age at Discharge.The Journal of pediatrics · 2021Observational
- Pharmacoepidemiology of Furosemide in the Neonatal Intensive Care Unit.Neonatology · 2020Article
- Variation in the use of diuretic therapy for infants with bronchopulmonary dysplasia.Pediatrics · 2013Article
- Routine use of diuretics in very-low birth-weight infants in the absence of supporting evidence.Journal of perinatology : official journal of the California Perinatal Association · 2011Article
- Impact of Early Versus Late Diuretic Exposure on Metabolic Bone Disease and Growth in Premature Neonates.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAGArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of this study was to describe factors influencing diuretic use by neonatologists caring for very low birth weight neonates. STUDY
designWe surveyed 400 U.S. neonatologists. Respondents made therapeutic decisions in clinical scenarios involving very low birth weight infants at 7, 14 and 28 days of age.
resultResponse rate was 39%. Diuretic therapy was chosen in 31% of scenario decisions, with pro re nata dosing selected early and regular dosing more common at later ages. Diuretic use was strongly associated with method of respiratory support, and was chosen less often by those also choosing fluid restriction and those concerned about patent ductus arteriosus risk. After adjusting for these factors, excessive weight gain, expected improvement in work of breathing and expected decrease in ventilator days were also associated with diuretic use.
conclusionThe extent of and expectations for diuretic therapy by neonatologists caring for very low birth weight neonates may exceed evidence for efficacy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.