Evidence map›Paper›PMID 21393849›Full record

ArticleActa crystallographica. Section F, Structural biology and crystallization communications2011

Crystallization of the Staphylococcus aureus MazF mRNA interferase.

Valentina Zorzini, Sarah Haesaerts, Niles P Donegan, Zhibiao Fu, Ambrose L Cheung, Nico A J van Nuland, Remy Loris

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section F, Structural biology and crystallization communications, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. YjbH Solubility Controls Spx inFrontiers in microbiology · 2020
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Valentina ZorziniStructural Biology Brussels, Department of Molecular and Cellular Interactions, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussel, Belgium.
Sarah Haesaerts
Niles P Donegan
Zhibiao Fu
Ambrose L Cheung
Nico A J van Nuland
Remy Loris
Vrije Universiteit Brussel · BEDartmouth College · US

Funding

The role of GraRS in resistance to cationic antimicrobial peptides in S. aureusR01AI091801 · NIAID · DARTMOUTH COLLEGE · PI CHEUNG, AMBROSE LIN YAU · 2011 to 2015
$2.4M
The toxin-antitoxin system of Staphylococcus aureus.R01AI076298 · NIAID · DARTMOUTH COLLEGE · PI CHEUNG, AMBROSE LIN YAU · 2009 to 2010
$790k
NIAID NIH HHS AI076298NIAID NIH HHS R01 AI076298NIAID NIH HHS R01 AI091801
6 · The paper itself

Abstract

mazEF modules encode toxin-antitoxin pairs that are involved in the bacterial stress response through controlled and specific degradation of mRNA. Staphylococcus aureus MazF and MazE constitute a unique toxin-antitoxin module under regulation of the sigB operon. A MazF-type mRNA interferase is combined with an antitoxin of unknown fold. Crystals of S. aureus MazF (SaMazF) were grown in space group P2(1)2(1)2(1). The crystals diffracted to 2.1 Å resolution and are likely to contain two SaMazF dimers in the asymmetric unit.

Indexed as

Bacterial ProteinsCrystallizationCrystallography, X-RayDNA-Binding ProteinsEndoribonucleasesMolecular Sequence DataRNA, MessengerStaphylococcus aureusBacterial ProteinsDNA-Binding ProteinsEndoribonucleasesRNA, Messenger

Identifiers

PMID21393849
PMCPMC3053169
OpenAlexW2038462954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.