ArticleClinical journal of the American Society of Nephrology : CJASN2011
Survival in pediatric dialysis and transplant patients.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- A comparative analysis of the starting modality of kidney replacement therapy amongst UK children and young adults and the association with all-cause mortality.Pediatric nephrology (Berlin, Germany) · 2026Article
- Trends in chronic dialysis practices and outcomes in North American children: a 30-year NAPRTCS registry analysis.Pediatric nephrology (Berlin, Germany) · 2026Article
- Article
- Acute Kidney Injury in Children: Classification, Recognition and Treatment Principles.Children (Basel, Switzerland) · 2024Review
- Medical and psychosocial outcomes in adolescents and young adults with childhood-onset end-stage kidney disease: a multicenter study in Japan.Clinical and experimental nephrology · 2023Article
- Cognitive and academic outcomes in children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2022Article
- The psychosocial needs of adolescent and young adult kidney transplant recipients, and associated interventions: a scoping review.BMC psychology · 2022Article
- Pediatric Onco-Nephrology: Time to Spread the Word-Part II: Long-Term Kidney Outcomes in Survivors of Childhood Malignancy and Malignancy after Kidney Transplant.Pediatric nephrology (Berlin, Germany) · 2022Article
- Epidemiology of pediatric chronic kidney disease/kidney failure: learning from registries and cohort studies.Pediatric nephrology (Berlin, Germany) · 2022Review
- Evaluation of the learning curve of pediatric kidney transplantation anesthesiaTurkish journal of medical sciences · 2021Article
- Pharmacokinetics of Vancomycin in Pediatric Patients Receiving Intermittent Hemodialysis or Hemodiafiltration.Kidney international reports · 2021Article
- Vaccination titres pre- and post-transplant in paediatric renal transplant recipients and the impact of immunosuppressive therapy.Pediatric nephrology (Berlin, Germany) · 2018Observational
- Survival in children requiring chronic renal replacement therapy.Pediatric nephrology (Berlin, Germany) · 2018Review
- Incomplete vaccination coverage in European children with end-stage kidney disease prior to renal transplantation.Pediatric nephrology (Berlin, Germany) · 2018Article
- Clinical outcomes and survival in pediatric patients initiating chronic dialysis: a report of the NAPRTCS registry.Pediatric nephrology (Berlin, Germany) · 2017Article
- Factors associated with cardiovascular target organ damage in children after renal transplantation.Pediatric nephrology (Berlin, Germany) · 2017Article
- Variation in estimated glomerular filtration rate at dialysis initiation in children.Pediatric nephrology (Berlin, Germany) · 2017Observational
- Prolonged respiratory disorder predicts adverse prognosis in infants with end-stage kidney disease.Pediatric nephrology (Berlin, Germany) · 2016Article
- Preemptive kidney transplantation is associated with survival benefits among pediatric patients with end-stage renal disease.Kidney international · 2016Article
- Lessons learned from the ESPN/ERA-EDTA Registry.Pediatric nephrology (Berlin, Germany) · 2016Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesLong-term follow-up data are few in children with ESRD. We sought to describe long-term survival, assess risk factors for death, and compare survival between two time periods in pediatric ESRD patients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We used a population-based retrospective cohort utilizing data from a national organ failure registry and from Canada's universal healthcare system. We included 843 children (ages, 0 to 18) initiating renal replacement therapy from 1992 to 2007 and followed them until death or date of last contact (median follow-up, 6.8 years; interquartile range, 3.0 to 10.6). We assessed risk factors for death and examined cause-specific mortality.
resultsDuring 5991 patient-years of follow-up, 107 (12.7%) patients died. Unadjusted cumulative survival for the cohort was: 91.7% (95% CI, 89.8 to 93.7%) at 5 years and 85.8% (95% CI, 82.8 to 88.8%) at 10 years. Among patients commencing dialysis, overall adjusted survival was poorest among those who started dialysis at age <1 year. No secular trends in survival were noted for either dialysis or transplant patients. The proportion of incident patients receiving pre-emptive transplantation increased over time. Pre-emptively transplanted patients did not demonstrate superior adjusted survival compared with those who spent >2 years on dialysis before transplant (hazard ratio, 1.53; 95% CI, 0.63 to 3.67).
conclusionsNo significant improvements in survival were observed among ESRD patients over the study period. Time with transplant function had the strongest association with survival. Pre-emptive transplantation was not associated with improved survival in adjusted models.
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