ArticleJournal of experimental botany2011
Induction of vacuolar invertase inhibitor mRNA in potato tubers contributes to cold-induced sweetening resistance and includes spliced hybrid mRNA variants.
Article in Journal of experimental botany, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 93 citations in OpenAlex.
- RNAi-mediated combinatorial silencing of StUGPase and StVInv genes effectively mitigates cold-induced sweetening in potato.Plant cell reports · 2025Article
- Alternative splicing-mediated regulation of a novel allele of Badh2 drives moderate accumulation of 2-AP in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Transcriptomic and metabolomic profiling of the potato plant response to zebra chip disease.PloS one · 2025Article
- Molecular dissection of an intronic enhancer governing cold-induced expression of the vacuolar invertase gene in potato.The Plant cell · 2024Article
- Genome-Wide Identification and Expression Patterns of Cucumber Invertases and Their Inhibitor Genes.International journal of molecular sciences · 2023Article
- Alternative splicing: transcriptional regulatory network in agroforestry.Frontiers in plant science · 2023Review
- Amelioration of cold-induced sweetening in potato by RNAi mediated silencing ofFrontiers in plant science · 2023Article
- The Plant Invertase/Pectin Methylesterase Inhibitor Superfamily.Frontiers in plant science · 2022Review
- Regulation of alternative splicing in response to temperature variation in plants.Journal of experimental botany · 2021Review
- The Landscape of Alternative Splicing Regulating Potassium Use Efficiency inFrontiers in plant science · 2021Article
- Cold storage reveals distinct metabolic perturbations in processing and non-processing cultivars of potato (Solanum tuberosum L.).Scientific reports · 2020Article
- Cell wall/vacuolar inhibitor of fructosidase 1 regulates ABA response and salt tolerance in Arabidopsis.Plant signaling & behavior · 2020Article
- In silico analysis of the structural diversity and interactions between invertases and invertase inhibitors from potato (3 Biotech · 2020Article
- PpINH1, an invertase inhibitor, interacts with vacuolar invertase PpVIN2 in regulating the chilling tolerance of peach fruit.Horticulture research · 2020Article
- Functional Characterization of Invertase Inhibitors PtC/VIF1 and 2 Revealed Their Involvements in the Defense Response to Fungal Pathogen inFrontiers in plant science · 2019Article
- Transcriptomic analysis of Aegilops tauschii during long-term salinity stress.Functional & integrative genomics · 2019Article
- Regional Heritability Mapping Provides Insights into Dry Matter Content in African White and Yellow Cassava Populations.The plant genome · 2018Article
- Identification and Functional Characterization of Sugarcane Invertase Inhibitor (Frontiers in plant science · 2018Article
- The roles of call wall invertase inhibitor in regulating chilling tolerance in tomato.BMC plant biology · 2017Article
- Heat stress affects carbohydrate metabolism during cold-induced sweetening of potato (Solanum tuberosum L.).Planta · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cold storage of tubers of potato (Solanum tuberosum L.) compromises tuber quality in many cultivars by the accumulation of hexose sugars in a process called cold-induced sweetening. This is caused by the breakdown of starch to sucrose, which is cleaved to glucose and fructose by vacuolar acid invertase. During processing of affected tubers, the high temperatures involved in baking and frying cause the Maillard reaction between reducing sugars and free amino acids, resulting in the accumulation of acrylamide. cDNA clones with deduced proteins homologous to known invertase inhibitors were isolated and the two most abundant forms, termed INH1 and INH2, were shown to possess apoplastic and vacuolar localization, respectively. The INH2 gene showed developmentally regulated alternative splicing, so, in addition to the INH2α transcript encoding the full-length protein, two hybrid mRNAs (INH2β*A and INH2β*B) that encoded deduced vacuolar invertase inhibitors with divergent C-termini were detected, the result of mRNA splicing of an upstream region of INH2 to a downstream region of INH1. Hybrid RNAs are common in animals, where they may add to the diversity of the proteome, but are rarely described in plants. During cold storage, INH2α and the hybrid INH2β mRNAs accumulated to higher abundance in cultivars resistant to cold-induced sweetening than in susceptible cultivars. Increased amounts of invertase inhibitor may contribute to the suppression of acid invertase activity and prevent cleavage of sucrose. Evidence for increased RNA splicing activity was detected in several resistant lines, a mechanism that in some circumstances may generate a range of proteins with additional functional capacity to aid adaptability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.