Evidence map›Paper›PMID 21392651›Full record

ReviewThe Veterinary clinics of North America. Equine practice2011

Adrenocortical insufficiency in horses and foals.

Kelsey A Hart, Michelle H Barton

Open access · greenAbstract readReview
In one paragraph

Review in The Veterinary clinics of North America. Equine practice, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Guideline
  2. Vasopressin stimulation testing in hospitalized foals.Journal of veterinary internal medicine · 2026
    Article
  3. Article
  4. Evaluation of Short-Term Stall Size Housing on the Behavior and Welfare of Domestic Horses (Equus caballus).Journal of the American Association for Laboratory Animal Science : JAALAS · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Dynamics of androgens in healthy and hospitalized newborn foals.Journal of veterinary internal medicine · 2021
    Article
  13. Article
  14. Article
  15. A review of equine sepsis.Equine veterinary education · 2015
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kelsey A HartDepartment of Large Animal Medicine, University of Georgia College of Veterinary Medicine, 501 DW Brooks Drive, Athens, GA 30602, USA. khart4@uga.edu
Michelle H Barton
Georgia College & State University · USUniversity of Georgia · US

Funding

Hydrocortisone replacement therapy in septic neonatal foalsF32GM086003 · NIGMS · UNIVERSITY OF GEORGIA · PI HART, KELSEY · 2008 to 2009
$117k
NIGMS NIH HHS F32 GM086003
6 · The paper itself

Abstract

The adrenal cortices produce various steroid hormones that play vital roles in several physiologic processes. Although permanent adrenocortical insufficiency is rare in all species, emerging evidence in both human and equine medicine suggests that transient reversible adrenocortical dysfunction resulting in cortisol insufficiency frequently develops during critical illness. This syndrome is termed relative adrenal insufficiency (RAI) or critical illness-related corticosteroid insufficiency (CIRCI) and can contribute substantially to morbidity and mortality associated with the primary disease. This review discusses the mechanisms, diagnosis, and clinical consequences of adrenocortical insufficiency, with particular focus on the current understanding of RAI/CIRCI in horses and foals.

Indexed as

Addison DiseaseAdrenal CortexAnimalsAnimals, NewbornFemaleHorse DiseasesHorsesHydrocortisoneMaleHydrocortisone

Identifiers

PMID21392651
PMCPMC3073730
OpenAlexW1986742217

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.