Evidence map›Paper›PMID 21392434›Full record

ArticleEmerging infectious diseases2011

Targeted drug-resistance testing strategy for multidrug-resistant tuberculosis detection, Lima, Peru, 2005-2008.

Gustavo E Velásquez, Martin Yagui, J Peter Cegielski, Luis Asencios, Jaime Bayona, Cesar Bonilla, Hector O Jave, Gloria Yale, Carmen Suárez, Sidney Atwood and 2 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Clinical characteristics, drug resistance, and treatment outcomes among tuberculosis patients with diabetes in Peru.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2013
    Article
  8. Impact of rapid drug susceptibility testing for tuberculosis: program experience in Lima, Peru.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2012
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gustavo E VelásquezBrigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Martin Yagui
J Peter Cegielski
Luis Asencios
Jaime Bayona
Cesar Bonilla
Hector O Jave
Gloria Yale
Carmen Suárez
Sidney Atwood
Carmen C Contreras
Sonya S Shin

Funding

Evaluation of MDR-TB Treatment Strategies in Lima, PeruK23AI054591 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI SHIN, SONYA S · 2004 to 2006
$331k
NIAID NIH HHS K23 AI054591
6 · The paper itself

Abstract

The Peruvian National Tuberculosis Control Program issued guidelines in 2006 specifying criteria for culture and drug-susceptibility testing (DST), including district-level rapid DST. All patients referred for culture and DST in 2 districts of Lima, Peru, during January 2005-November 2008 were monitored prospectively. Of 1,846 patients, 1,241 (67.2%) had complete DST results for isoniazid and rifampin; 419 (33.8%) patients had multidrug-resistant (MDR) TB at the time of referral. Among patients with new smear-positive TB, household contact and suspected category I failure were associated with MDR TB, compared with concurrent regional surveillance data. Among previously treated patients with smear-positive TB, adult household contact, suspected category II failure, early relapse after category I, and multiple previous TB treatments were associated with MDR TB, compared with concurrent regional surveillance data. The proportion of MDR TB detected by using guidelines was higher than that detected by a concurrent national drug-resistance survey, indicating that the strategy effectively identified patients for DST.

Indexed as

Drug Resistance, Multiple, BacterialAntitubercular AgentsHumansIsoniazidMass ScreeningMicrobial Sensitivity TestsMycobacterium tuberculosisPeruPopulation SurveillancePractice Guidelines as TopicPrevalenceRifampinTuberculosis, Multidrug-ResistantAntitubercular AgentsIsoniazidRifampin

Identifiers

PMID21392434
PMCPMC3166030

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.