Evidence map›Paper›PMID 21392401›Full record

ReviewActa veterinaria Scandinavica2011

Adaptation of mammalian host-pathogen interactions in a changing arctic environment.

Karsten Hueffer, Todd M O'Hara, Erich H Follmann

Open access · goldAbstract readReview
In one paragraph

Review in Acta veterinaria Scandinavica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Journal of fungi (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
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  9. Article
  10. Review
  11. Review
  12. Review
  13. One health in the circumpolar North.International journal of circumpolar health · 2019
    Article
  14. Human Seroprevalence to 11 Zoonotic Pathogens in the U.S. Arctic, Alaska.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2019
    Article
  15. Rabies in Alaska, from the past to an uncertain future.International journal of circumpolar health · 2018
    Review
  16. Article
  17. Water, sanitation, pollution, and health in the Arctic.Environmental science and pollution research international · 2018
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Karsten HuefferMolecular Ecology of Infectious Agents Laboratory University of Alaska Fairbanks, 902 N, Koyukuk Dr,, Fairbanks AK 99775, USA. khueffer@alaska.edu
Todd M O'Hara
Erich H Follmann
University of Alaska Fairbanks · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many arctic mammals are adapted to live year-round in extreme environments with low winter temperatures and great seasonal variations in key variables (e.g. sunlight, food, temperature, moisture). The interaction between hosts and pathogens in high northern latitudes is not very well understood with respect to intra-annual cycles (seasons). The annual cycles of interacting pathogen and host biology is regulated in part by highly synchronized temperature and photoperiod changes during seasonal transitions (e.g., freezeup and breakup). With a warming climate, only one of these key biological cues will undergo drastic changes, while the other will remain fixed. This uncoupling can theoretically have drastic consequences on host-pathogen interactions. These poorly understood cues together with a changing climate by itself will challenge host populations that are adapted to pathogens under the historic and current climate regime. We will review adaptations of both host and pathogens to the extreme conditions at high latitudes and explore some potential consequences of rapid changes in the Arctic.

Indexed as

Adaptation, PhysiologicalMammalsAnimalsArctic RegionsClimate ChangeCold TemperatureEnvironmentHost-Pathogen Interactions

Identifiers

PMID21392401
PMCPMC3061946
OpenAlexW2098386984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.