Evidence map›Paper›PMID 21391305›Full record

ReviewWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

Current trends in nanobiosensor technology.

Leon M Bellan, Diana Wu, Robert S Langer

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Review
  3. Nanotechnological Interventions in Agriculture.Nanomaterials (Basel, Switzerland) · 2022
    Review
  4. Review
  5. Nanotechnology: A Potential Weapon to Fight against COVID-19.Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems · 2022
    Review
  6. Review
  7. Review
  8. Nanoparticle approaches against SARS-CoV-2 infection.Current opinion in solid state & materials science · 2021
    Article
  9. Review
  10. Article
  11. Pathogenic Virus Detection by Optical Nanobiosensors.Cell reports. Physical science · 2021
    Review
  12. Article
  13. Review
  14. Nanomaterial-based biosensors for detection of pathogenic virus.Trends in analytical chemistry : TRAC · 2017
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Leon M BellanDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. Lbellan@mit.edu
Diana Wu
Robert S Langer

Funding

Microchip Drug Delivery SystemR01EB006365 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LANGER, ROBERT SAMUEL · 2007 to 2011
$5.8M
3D Microvascular Networks in Biomaterials Fabricated with Sacrificial StructuresF32EB011866 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELLAN, LEON MARCEL · 2010 to 2010
$50k
NIBIB NIH HHS EB006365NIBIB NIH HHS F32 EB011866NIBIB NIH HHS F32EB011866NIBIB NIH HHS R01 EB006365
6 · The paper itself

Abstract

The development of tools and processes used to fabricate, measure, and image nanoscale objects has lead to a wide range of work devoted to producing sensors that interact with extremely small numbers (or an extremely small concentration) of analyte molecules. These advances are particularly exciting in the context of biosensing, where the demands for low concentration detection and high specificity are great. Nanoscale biosensors, or nanobiosensors, provide researchers with an unprecedented level of sensitivity, often to the single molecule level. The use of biomolecule-functionalized surfaces can dramatically boost the specificity of the detection system, but can also yield reproducibility problems and increased complexity. Several nanobiosensor architectures based on mechanical devices, optical resonators, functionalized nanoparticles, nanowires, nanotubes, and nanofibers have been demonstrated in the lab. As nanobiosensor technology becomes more refined and reliable, it is likely it will eventually make its way from the lab to the clinic, where future lab-on-a-chip devices incorporating an array of nanobiosensors could be used for rapid screening of a wide variety of analytes at low cost using small samples of patient material.

Indexed as

Biosensing TechniquesNanostructuresNanotechnology

Identifiers

PMID21391305
PMCPMC4126610

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.